Skip to content
Licensed Unlicensed Requires Authentication Published by De Gruyter June 21, 2011

A prospective clinical pilot-trial comparing the effect of an optimized mixed diet versus a flexible low-glycemic index diet on nutrient intake and HbA1c levels in children with type 1 diabetes

  • Jan Marquard EMAIL logo , Anna Stahl , Christian Lerch , Mareen Wolters , Maike Grotzke-Leweling , Ertan Mayatepek and Thomas Meissner


Background: Low-glycemic index (GI) diet vs. high-GI diet improves glycemic control, but it is not clear whether a low-GI diet is superior to an optimized mixed diet (OMD).

Methods: This was a 12-week parallel-group pilot-trial including 17 children with type 1 diabetes. A separate dietary education into the allocated diet (OMD vs. low-GI) was performed. Nutrition was recorded by means of a three-day dietary record.

Objectives: The primary objective was to determine the macro- and micronutrient composition of the different diets, the secondary objective was to determine the short-term effect on HbA1c levels.

Results: In the low-GI group carbohydrate intake decreased, fat intake increased by trend. In the OMD group fat and energy intake decreased. No changes of HbA1c levels between the groups were observed.

Conclusion: OMD could have positive effects in overweight and obese diabetic children, since a reduction in fat and energy intake can be achieved. The findings of this pilot-trial suggest that OMD could be superior to a low-GI diet.

Corresponding author: Jan Marquard, Department of General Pediatrics, University Children’s Hospital Duesseldorf, Moorenstrasse 5, 40225 Duesseldorf, Germany Phone: +49 211 8117711, Fax: +49 211 8119512

Published Online: 2011-06-21
Published in Print: 2011-08-01

©2011 by Walter de Gruyter Berlin Boston

Downloaded on 22.9.2023 from
Scroll to top button