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Licensed Unlicensed Requires Authentication Published by De Gruyter March 18, 2010

Clinical characteristics of nosocomial infections in neonatal intensive care unit in eastern China

  • Xue-Feng Xu , Xiao-Lu Ma , Zheng Chen , Li-Ping Shi and Li-Zhong Du
From the journal


A retrospective cohort study on nosocomial infections (NI) in the neonatal intensive care unit (NICU) was performed in the Children's Hospital of Zhejiang University, Hangzhou district, China. The most common infection site was pneumonia and bloodstream infection. Low admission age, long NICU stay, and mechanical ventilation were significant risk factors for NI. Klebsiella pneumoniae was the most common pathogen, followed by Acinetobacter baumannii, Staphylococcus epidermidi, Pseudomonas aeruginosa, Enterobacter cloacae, and Stenotrophomonas maltophilia. Antibiotic resistance of the isolated bacterium was high. In conclusion, this study described the clinical characteristics of NI in a Chinese NICU, which might contribute to implementation of more effective therapeutic and preventive strategies.

Corresponding author: Li-Zhong Du Department of Neonatology The Children's Hospital Zhejiang University School of Medicine Hangzhou 310003 P.R. China Tel.: +86 571 87061007 ext 2222 Fax: +86 571 87033296

Received: 2009-10-15
Revised: 2010-1-6
Accepted: 2010-1-12
Published Online: 2010-03-18
Published Online: 2010-03-18
Published in Print: 2010-07-01

©2010 by Walter de Gruyter Berlin New York

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