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BY-NC-ND 3.0 license Open Access Published by De Gruyter Open Access October 8, 2014

Isolated myeloid sarcoma of the neck and chest: differential diagnosis and therapeutic approach

Predrag Djurdjevic, Danijela Jovanovic and Darko Antic
From the journal Open Medicine


In this article, we present the case of a 57-yearold man with cervical and mediastinal tumor mass, normal blood count as well as virusological status. Cervical tumor tissue biopsy revealed cells positive for CD34, CD13, LCA, CD33, and CD163 but negative for T-cell and B-cell markers, NK-cell markers, plasmacytic markers and anaplastic large cell lymphoma markers. These features were consistent with myeloid sarcoma of the neck with involvement of the mediastinum. We discussed differential diagnosis and therapy of isolated myeloid sarcoma and suggest that clinical presentation, cell morphology, complete immunophenotype, and specific genotypic lesions in some cases, must be evaluated.


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Received: 2013-10-8
Accepted: 2014-6-4
Published Online: 2014-10-8
Published in Print: 2015-1-1

© 2015 Predrag Djurdjevic, Danijela Jovanovic, Darko Antic

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 3.0 License.

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