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BY 4.0 license Open Access Published by De Gruyter Open Access December 31, 2021

Synthesis and characterization of PCU@C-Ag/AgCl nanoparticles as an antimicrobial material for respiratory tract infection

  • Senthilkumar Palanisamy EMAIL logo , Kalaivani Subramanian , Lerince Godrina Bennet , Janani Ambrose , Aganiya Gopalakrishnan , Sudhagar Babu , Ranjithkumar Rajamani , Niraj Kumar Jha , Soumya Pandit , Sachin Kumar Singh , Kamal Dua and Piyush Kumar Gupta EMAIL logo
From the journal Nanofabrication


The pregnant cow urine (PCU) is an active source of antimicrobial agents that is used for fabricating chitosan coated Ag/AgCl nanoparticles (NPs) in the present study. These PCU@C-Ag/AgCl NPs were physicochemically characterized and evaluated for antimicrobial activity against selected respiratory tract infection (RTI) pathogens. The absorption band around 420 nm in UV-Visible spectrum indicated the presence of Ag NPs. The spherical shape of NPs was observed using TEM. Also, the crystalline structure was confirmed using the XRD pattern. The PCU@C-Ag/AgCl NPs showed strong antimicrobial activity against all tested RTI pathogens. In addition, FESEM analysis showed morphological changes in RTI bacterial pathogens. Thereby, PCU@C-Ag/AgCl NPs may be used as an antimicrobial material to treat RTIs in near future at clinical level.


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Received: 2021-10-20
Accepted: 2021-12-03
Published Online: 2021-12-31

© 2021 Senthilkumar Palanisamy et al., published by De Gruyter

This work is licensed under the Creative Commons Attribution 4.0 International License.

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