Accessible Requires Authentication Published by De Gruyter November 21, 2014

Flexible polyvinyl alcohol/2-hydroxypropanoic acid films: effect of residual acetyl moieties on mechanical, thermal and antibacterial properties

Martina Hrabalikova, Martha Merchan, Solongo Ganbold, Vladimir Sedlarik, Pavel Valasek and Petr Saha


This work ascertains the effect of the degree of hydrolysis of polyvinyl alcohol under extended interaction with 2-hydroxypropanoic acid (lactic acid). Systems based on three different types of polyvinyl alcohol matrices (of hydrolysis degree 80, 88 and 98 mol%) and lactic acid were characterized according to their physicochemical, mechanical and thermal properties. An agar diffusion test and the dilution and spread plate technique were conducted to facilitate antibacterial activity to counteract Staphylococcus aureus and Escherichia coli. A mathematical model was applied to the experimental data to estimate the antibacterial efficacy of the resultant flexible films.

Corresponding author: Vladimir Sedlarik, Centre of Polymer Systems, Tomas Bata University in Zlin, nam. T. G. Masaryka 5555, 760 01 Zlin, Czech Republic, e-mail:


This article was written with the support of Operational Program Research and Development for Innovations co-funded by the EDF and national budget of Czech Republic, within the framework of the project Centre of Polymer Systems (reg. number: CZ. and of Operational Program Education for Competitiveness co-funded by the European Social Fund (ESF) and the national budget of Czech Republic, within the framework of the project Advance Theoretical and Experimental Studies of Polymer Systems (reg. number: CZ.1.07/2.3.00/20.0104). This work was also co-funded by a project of the Ministry of Agriculture of the Czech Republic: The National Agency for Agriculture Research (Grant No. QJ1310254), the Ministry of Education, Youth and Sports of the Czech Republic (projects LE12002) and the Internal Grant Agency of Tomas Bata University in Zlín (Grant No. IGA/FT/2014/012).


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Received: 2014-5-12
Accepted: 2014-9-26
Published Online: 2014-11-21
Published in Print: 2015-5-1

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