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The consequences of removing fluorinated compounds from rigid contact lenses

  • Mark D. Eddleston EMAIL logo , Levente Raduly , Tristan T. Tapper , Reece J. Hughes , Gareth M. Browne und Martin J. Conway
Aus der Zeitschrift Journal of Polymer Engineering


Fluorine free analogues of three commercially available rigid contact lens materials were prepared by replacing the fluorinated component, hexafluoroisopropyl methacrylate (HFPM), with the widely used, non-fluorinated monomers methyl methacrylate (MMA) and 3-methacryloxypropyltris-(trimethylsiloxy)silane (TRIS). The properties of the commercial materials and analogues were measured and compared. The oxygen permeabilities of the MMA analogues were found to be significantly lower than those of the commercial materials, decreasing by 87 % on average, while the TRIS analogues lacked sufficient hardness, dimensional stability and lipid deposit resistance to be viable for use in rigid contact lenses. Analogues prepared using a 1:1 mixture of MMA and TRIS had the best overall combination of properties, but were still on average 47 % less permeable to oxygen and also significantly less resistant to lipid deposition. The analogues prepared in this study did not adequately replicate the performance of marketed, fluorine containing rigid contact lens materials. These observations give an indication of the challenges that would face contact lens material manufacturers in preparing rigid lens polymers without the use of fluorinated species. A reduction in effectiveness would be almost inevitable, and would be expected to have a negative impact on the safety and eye health of rigid contact lens patients.

Corresponding author: Mark D. Eddleston, Euromcontact, Avenue des Arts 56, 1000 Brussels, Belgium, E-mail:


The authors thank Dr Matthew Rowland for providing the lipid deposition methodology.

  1. Author contributions: All the authors have accepted responsibility for the entire content of this submitted manuscript and approved submission.

  2. Research funding: None declared.

  3. Conflict of interest statement: The authors declare that they have no conflicts of interest regarding this article.


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Received: 2022-08-02
Accepted: 2023-04-17
Published Online: 2023-05-11

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