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Licensed Unlicensed Requires Authentication Published by De Gruyter September 6, 2014

The influence of vapor pressure of chemicals on dermal penetration

  • Sarah Gilpin EMAIL logo


Dermal exposure is an important route of entry for chemicals in occupational and consumer settings. Key to this exposure is the penetration of the skin’s barrier, and key to this penetration is a chemical’s vapor pressure. Until now, vapor pressure and its effects on the skin have yet to be widely studied. This review aims to provide some historical background on early work on dermal penetration for volatile materials, which has helped form later research into the effects of vapor pressure on chemical risk assessment for dermal exposures. This review should be the start of an investigation into more in-depth coverage of vapor pressure and current prediction models.

Corresponding author: Sarah Gilpin, PhD, University of Minnesota and Kao USA, 1404 E McMillan St., Cincinnati, OH 45206, USA, Phone: +513-332-1660, E-mail:


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Received: 2014-7-29
Accepted: 2014-7-31
Published Online: 2014-9-6
Published in Print: 2014-8-1

©2014 by De Gruyter

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