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Systematic review: the impact of socioeconomic factors on Aedes aegypti mosquito distribution in the mainland United States

Whitney M. Holeva-Eklund, Timothy K. Behrens and Crystal M. Hepp

Abstract

Aedes aegypti mosquitoes are primary vectors of dengue, yellow fever, chikungunya and Zika viruses. Ae. aegypti is highly anthropophilic and relies nearly exclusively on human blood meals and habitats for reproduction. Socioeconomic factors may be associated with the spread of Ae. aegypti due to their close relationship with humans. This paper describes and summarizes the published literature on the association between socioeconomic variables and the distribution of Ae. aegypti mosquitoes in the mainland United States. A comprehensive search of PubMed/Medline, Scopus, Web of Science, and EBSCO Academic Search Complete through June 12, 2019 was used to retrieve all articles published in English on the association of socioeconomic factors and the distribution of Ae. aegypti mosquitoes. Additionally, a hand search of mosquito control association websites was conducted in an attempt to identify relevant grey literature. Articles were screened for eligibility using the process described in the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines. Initially, 3,493 articles were identified through the database searches and previously known literature. After checking for duplicates, 2,145 articles remained. 570 additional records were identified through the grey literature search for a total of 2,715 articles. These articles were screened for eligibility using their titles and abstracts, and 2,677 articles were excluded for not meeting the eligibility criteria. Finally, the full text for each of the remaining articles (n=38) was read to determine eligibility. Through this screening process, 11 articles were identified for inclusion in this review. The findings for these 11 studies revealed inconsistent relationships between the studied socioeconomic factors and the distribution and abundance of Ae. aegypti. The findings of this review suggest a gap in the literature and understanding of the association between anthropogenic factors and the distribution of Ae. aegypti that could hinder efforts to implement effective public health prevention and control strategies should a disease outbreak occur.


Corresponding author: Whitney M. Holeva-Eklund, Department of Health Sciences, Northern Arizona University, Flagstaff, Arizona, USA; School of Informatics, Computing, and Cyber Systems, Northern Arizona University, Flagstaff, Arizona, USA, E-mail:

Funding source: Pacific Southwest Center of Excellence in Vector-Borne Diseases, funded by the US Centers for Disease Control and Prevention

Award Identifier / Grant number: 1U01CK000516

Funding source: Arizona Technology Research and Initiative Fund

Funding source: Arizona Biomedical Research Center

  1. Research Funding: This work has been supported by the following funds awarded to CMH: New Investigator Award from the Arizona Biomedical Research Center, start-up funds from the Arizona Technology Research and Initiative Fund, and a training grant to support WHE, from the Pacific Southwest Regional Center of Excellence for Vector-Borne Diseases funded by the U.S. Centers for Disease Control and Prevention (Cooperative Agreement 1U01CK000516).

  2. Author contributions: All authors have accepted responsibility for the entire content of this manuscript and approved its submission.

  3. Competing interests: The authors declare no conflict of interest. The funders had no role in the design of the study; in the collection, analyses, or interpretation of data; in the writing of the manuscript, or in the decision to publish the results.

  4. Informed Consent: Informed consent is not applicable.

  5. Ethical approval: The conducted research is not related to either human or animal use.

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Supplementary material

The online version of this article offers supplementary material (https://doi.org/10.1515/REVEH-2020-0028).


Received: 2020-02-27
Accepted: 2020-07-08
Published Online: 2020-08-27
Published in Print: 2021-03-26

© 2020 Walter de Gruyter GmbH, Berlin/Boston

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