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Licensed Unlicensed Requires Authentication Published by De Gruyter March 24, 2022

Music affects functional brain connectivity and is effective in the treatment of neurological disorders

  • Luisa Speranza , Salvatore Pulcrano ORCID logo EMAIL logo , Carla Perrone-Capano , Umberto di Porzio and Floriana Volpicelli ORCID logo

Abstract

In a million years, under the pressure of natural selection, hominins have acquired the abilities for vocal learning, music, and language. Music is a relevant human activity, highly effective in enhancing sociality, is a universal experience common to all known human cultures, although it varies in rhythmic and melodic complexity. It has been part of human life since the beginning of our history, or almost, and it strengthens the mother-baby relation even within the mother’s womb. Music engages multiple cognitive functions, and promotes attention, concentration, imagination, creativity, elicits memories and emotions, and stimulates imagination, and harmony of movement. It changes the chemistry of the brain, by inducing the release of neurotransmitters and hormones (dopamine, serotonin, and oxytocin) and activates the reward and prosocial systems. In addition, music is also used to develop new therapies necessary to alleviate severe illness, especially neurological disorders, and brain injuries.


Corresponding author: Salvatore Pulcrano, Institute of Genetics and Biophysics, “Adriano Buzzati-Traverso”, C.N.R., Via P. Castellino 111, 80131 Naples, Italy; and Department of Pharmacy, School of Medicine and Surgery, University of Naples Federico II, 80131 Naples, Italy, E-mail:

Funding source: Regione Campania http://dx.doi.org/10.13039/501100003852

Award Identifier / Grant number: POR Campania FESR 2014/2020 - Project N. B61G18000

  1. Author contribution: All the authors have accepted responsibility for the entire content of this submitted manuscript and approved submission.

  2. Research funding: This work was supported by “POR Campania FESR 2014/2020” (Project N. B61G18000470007) from Regione Campania, Italy, Progetto 000005_2018_RARE.PLAT.NET and 000005_BUDGET_ECONOMICO_RICERCA_2020.

  3. Conflict of interest statement: The authors declare that the review was conducted in the absence of any commercial or financial relationship that could be constructed as a potential conflict of interest.

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Received: 2021-10-09
Revised: 2022-02-23
Accepted: 2022-02-25
Published Online: 2022-03-24
Published in Print: 2022-10-26

© 2022 Walter de Gruyter GmbH, Berlin/Boston

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