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Licensed Unlicensed Requires Authentication Published by De Gruyter October 11, 2014

Electro-Mechanical Coupling in a One-Dimensional Model of Heart Muscle fiber

Leonid B. Katsnelson, Natalia A. Vikulova, Alexander G. Kursanov, Olga E. Solovyova and Vladimir S. Markhasin

Abstract

We developed a mathematical model that describes heart muscle fiber as a one-dimensional continuous medium of electrically and mechanically coupled cardiomyocytes through which electrical excitation propagates and initiates muscle contraction. The generic model simulates bilateral relations between the electrical and the mechanical activity of cardiomyocytes in the tissue and accounts for both intracellular and intercellular electro-mechanical couplings and mechano-electric feedback mechanisms.

Received: 2014-4-25
Accepted: 2014-6-25
Published Online: 2014-10-11
Published in Print: 2014-10-1

© 2014 by Walter de Gruyter Berlin/Boston