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Licensed Unlicensed Requires Authentication Published by Oldenbourg Wissenschaftsverlag October 1, 2015

Portable device design for in-vitro muscle tissue monitoring

Entwurf eines tragbaren Bioimpedanz-Messgeräts für in-vitro Muskelgewebeüberwachung
Dhouha Bouchaala

Dhouha Bouchaala obtained her master degree (2009) and engineer's degree (2008) in electrical engineering from the National Engineering School of Sfax (ENIS), Tunisia. She is currently a PhD student at Chemnitz University of Technology, Germany and National Engineering School of Sfax, Tunisia. Her research is centered of bioimpedance measurement, voltage controlled current source and excitation signals.

Technische Universität Chemnitz, Fakultät für Elektrotechnik und Informationstechnik, Deutschland

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, Mahdi Guermazi

Mahdi Guermazi obtained his master degree (2008) in electrical engineering from the National Engineering School of Sfax (ENIS), Tunisia. He is currently a PhD student at Chemnitz University of Technology, Germany and National Engineering School of Sfax, Tunisia. His research is centered on impedance spectroscopy, meat measurement and modeling.

Technische Universität Chemnitz, Fakultät für Elektrotechnik und Informationstechnik, Deutschland

, Olfa Kanoun

Olfa Kanoun is a full professor for measurement and sensor technology at Chemnitz University of Technology, Germany. Her main research fields are: Impedance spectroscopy, energy harvesting and micro and nano sensors. She received her PhD degree from the institute for measurement and automation at the University of Bundeswehr Munich. She was awarded in 2001 by the German Commission of Professors for Measurement Technology (AHMT. e.V). She is the cjair of the German IEEE Instrumentation and Measurement Chapter since 2005. She has published four books, more than 30 journal papers and 150 conference papers.

Technische Universität Chemnitz, Professur für Mess- und Sensortechnik, Deutschland

and Nabil Derbel

Nabil Derbel is a full professor for control and Energy Management laboratory at National Engineering School of Sfax, Tunisia. His main research fields are: optimal control, complex systems, fuzzy logic, neural networks and genetic algorithms. He received his PhD degree from Control and Analyze of Systems laboratory in Toulouse, France (1989). He has published more than 50 journal papers and more than 300 conference papers.

University of Sfax, National Engineering School of Sfax, Tunisia

From the journal tm - Technisches Messen

Abstract

Experimental investigations were carried out in order to identify the portable device requirements for in-vitro muscle tissue monitoring over time. Based on these investigations, specifications for the measurement system were defined considering the type and amplitude of excitation signals (500 mV), frequency range (1 kHz–10 MHz) and impedance range (10 Ω–4 kΩ). For these requirements, a portable device structure is proposed based on the magnitude ratio and phase difference detection using a gain phase detector. To fulfill the requirements of the gain phase detector circuit's inputs, an interface circuit is proposed with an error lower than 0.09% from 2 mV up to 200 mV.

Zusammenfassung

Basierend auf experimentelle Untersuchungen wurden die Anforderungen für die In-vitro Untersuchung biologischer Muskelgewebe bei verschiedenen Muskelarten identifiziert. Darauf basierend ließen sich die Spezifikationen für das Messsystem bezüglich der Art und der Amplitude notwendiger Anregungssignale (500 mV), des Frequenzbereichs (1 kHz–10 MHz) und des Impedanzbereiches (10 Ω–4 kΩ) bestimmen. Für diese Anforderungen wurde ein Entwurf für ein tragbares Messsystem vorgeschlagen. Für die Impedanzmessung wird hierbei ein Verstärkung-Phasen-Detektor genutzt. Um die Anforderungen für die Eingangssignale des Verstärkung-Phasen-Detektor zu erfüllen, wurde eine elektronische Schnittstelle vorgeschlagen, die ein Fehler unter 0.09% von 2 mV bis 200 mV.

About the authors

Dhouha Bouchaala

Dhouha Bouchaala obtained her master degree (2009) and engineer's degree (2008) in electrical engineering from the National Engineering School of Sfax (ENIS), Tunisia. She is currently a PhD student at Chemnitz University of Technology, Germany and National Engineering School of Sfax, Tunisia. Her research is centered of bioimpedance measurement, voltage controlled current source and excitation signals.

Technische Universität Chemnitz, Fakultät für Elektrotechnik und Informationstechnik, Deutschland

Mahdi Guermazi

Mahdi Guermazi obtained his master degree (2008) in electrical engineering from the National Engineering School of Sfax (ENIS), Tunisia. He is currently a PhD student at Chemnitz University of Technology, Germany and National Engineering School of Sfax, Tunisia. His research is centered on impedance spectroscopy, meat measurement and modeling.

Technische Universität Chemnitz, Fakultät für Elektrotechnik und Informationstechnik, Deutschland

Olfa Kanoun

Olfa Kanoun is a full professor for measurement and sensor technology at Chemnitz University of Technology, Germany. Her main research fields are: Impedance spectroscopy, energy harvesting and micro and nano sensors. She received her PhD degree from the institute for measurement and automation at the University of Bundeswehr Munich. She was awarded in 2001 by the German Commission of Professors for Measurement Technology (AHMT. e.V). She is the cjair of the German IEEE Instrumentation and Measurement Chapter since 2005. She has published four books, more than 30 journal papers and 150 conference papers.

Technische Universität Chemnitz, Professur für Mess- und Sensortechnik, Deutschland

Nabil Derbel

Nabil Derbel is a full professor for control and Energy Management laboratory at National Engineering School of Sfax, Tunisia. His main research fields are: optimal control, complex systems, fuzzy logic, neural networks and genetic algorithms. He received his PhD degree from Control and Analyze of Systems laboratory in Toulouse, France (1989). He has published more than 50 journal papers and more than 300 conference papers.

University of Sfax, National Engineering School of Sfax, Tunisia

Received: 2015-6-22
Revised: 2015-8-21
Accepted: 2015-8-21
Published Online: 2015-10-1
Published in Print: 2015-10-28

©2015 Walter de Gruyter Berlin/Boston

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