Myeloarchitectonic maps of the human cerebral cortex registered to surface and sections of a standard atlas brain

Abstract C. and O. Vogt had set up a research program with the aim of establishing a detailed cartography of the medullary fiber distribution of the human brain. As part of this program, around 200 cortical fields were differentiated based on their myeloarchitectural characteristics and mapped with regard to their exact location in the isocortex. The typical features were graphically documented and classified by a sophisticated linguistic coding. Their results have only recently received adequate attention and applications. The reasons for the revival of this spectrum of their research include interest in the myeloarchitecture of the cortex as a differentiating feature of the cortex architecture and function, as well as the importance for advanced imaging methodologies, particularly tractography and molecular imaging. Here, we describe our approach to exploit the original work of the Vogts and their co-workers to construct a myeloarchitectonic map that is referenced to the Atlas of the Human Brain (AHB) in standard space. We developed a semi-automatic pipeline for processing and integrating the various original maps into a single coherent map. To optimize the precision of the registration between the published maps and the AHB, we augmented the maps with topographic landmarks of the brains that were originally analyzed. Registration of all maps into the AHB opened several possibilities. First, for the majority of the fields, multiple maps from different authors are available, which allows for sophisticated statistical integration, for example, unification with a label-fusion technique. Second, each field in the myeloarchitectonic surface map can be visualized on the myelin-stained cross-section of the AHB at the best possible correspondence. The features of each field can be correlated with the fiber-stained cross-sections in the AHB and with the extensive published materials from the Vogt school and, if necessary, corrected. Third, mapping to the AHB allows the relationship between fiber characteristics of the cortex and the subcortex to be examined. Fourth, the cytoarchitectonic maps from Brodmann and von Economo and Koskinas, which are also registered to the AHB, can be compared. This option allows the study of the correspondence between cyto- and myeloarchitecture in each field. Finally, by using our “stripe” technology – where any other feature registered to the same space can be directly compared owing to the linear and parallel representation of the correlated cortex segments – this map becomes part of a multidimensional co-registration platform.

L-1 o narrow; L-1a+b with numerous Ef: therefore slightly trizonal.L-4-6 is considerably richer in Ef and Gf than F50 (5b is relatively prominent in the caudal part).L-6aαless prominent.The individual Gf (basic fibers) and Ef in all layers are of a somewhat coarse type.
Unistriate, belongs to the fiber rich group, euradiate

Div. subquadrizonalis
The L-1°is thicker, and the L-1a is always clearly distinguished from L-1b due to its paucity in Gf and especially Ef.

3
A. propetrizonalis L-1a is still relatively rich in fibres.All layers contain fewer Gf than F2 or F1.Ef in layers 4-6 are thinner as compared with F2, but thicker compared with F1.
F3 cannot be distinguished from 4 with certainty.
unistriate, poor fiber category, slightly euradiate, L-4 = 5b and thinner Ef in layers 3-6.The radii are more developed than in F-10 and in F-11.
In comparison with F1, F4 contains significantly less fibers in layers 1b-6bα than F-50 and F-33 but these fibers are coarser.
unistriate, poor fiber category, slightly euradiate, L-4 = 5b (Continued) Myelo-map on standard atlas  I A. subquadrizonalis dives H68 (ext) F5 is characterized by a greater abundance of fibers in all layers compared with F4.
unistriate, poor fiber category, slightly euradiate, L-4 = 5b Div.quadrizonalis Sublayer 1 o is even thicker, and the L-1b contains thicker Ef than the Divisio subquadrizonalis 6 A. propeultratangentialis S2, VV Difficult to separate from F4. F 6 contains more fibres in all layers and more developed radii if compared with F4.
F 6 contains numerous thick Ef in the L-1c and therefore resembles the ultratangential subregion.In comparison with F4, F6 contains less fibres in layers 2-6.
In L-1c numerous thick individual fibers appear, resulting in an approximation of the Subregio ultratangentialis.S2: euradiate.
unistriate, poor fiber category, medioradiate, L-4 = 5b; 7 A. quadrizonalis pauper.VV In L-1 fewer and thinner Gf than are present than in the adjacent areas F4 and F6.In L-2-6 there are also fewer and thinner fibers.In comparison with F4 and F6 this field (7) has a smaller number of thin Gf in the L-1 as well as smaller numbers of thin Ef in layers 2-6.

8
A. quadrizonalis intermedia F8 contains more fibers than F7.L-1 is clearly more fibrous than in F4 and F11, but significantly less fibrous than in F62 and F66.S2: mediodiate.
unistriate, poor fiber category, medio-to euradiate, L-4 = 5b 9 A. quadrizonalis dives S2, VV F9 is located at the transition to the Regio unitostriata, shows a greater abundance of fibers than the other areas of the Divisio quadrizonalis, whereby it represents a transition towards the unitostriate region (especially towards its F62).
F9 is subquadrizonal; similar to F8 but with coarser Ef in the sublayer 1b and in L6.
Generally less fibrous than F62.
Its Ef in layers 3-6 are thinner compared to the F3, but coarser than in F4 and F6.
Compared to F13 L-1 has fewer but L-4 shows more fibers.
unistriate, poor fiber category, medioradiate, L-4 = 5b 12 A. ultratangentialis propetrizonalis VV Ef are missing in L-1a, but plenty in L-1b; L-1c contains relatively many Gf.L-2 shows numerous thick individual fibers.The other layers are characterized by a very low fiber content, but L-4 stands out quite clearly from L-3 and 5a.
F12 compares to F21 but shows more ultratangential fibers in L-1c and 2.
Compared with F15 L-1a+b has somewhat fewer fibers, L-1c more (ultratangential) fibers.Radii are as poorly developed as in F15.
unistriate, poor fiber category, infraradiate, L-4 = less intense than 5b Div.supraradiataThis Divisio has very many horizontal Gf in L-1c and L-2, very thick Ef in L-1c-5a.L-3b-6aα are rudimentary so that L-5a does not stand out at all; in L-3a thin radial fibers are seen.
L-1c contains numerous Gf; the layers 1-5a (caudally also sublayer 1a+b) exhibit many very thick (ultratangential) Ef.Layers 3b to 6aα are rudimentary, making it difficult to delineate L-5a.This area contains even more radial fibers in L-2 and even thinner radial bundles in L-3a.
At the bottom of the sulcus corporis callosi, the Area 14 is present in its rudimentary form and continues around the genu corporis callosi in the caudal direction.At the caudal border of the Pars frontalis it undergoes a characteristic architectonic transformation -the lateral Lancisi's stria appears here.

R. UNISTRIATA EURADIATA INFRARADIATA
Areae 15-32 This region coincides with the cytoarchitectural region of the same name.

16
A. dives S2 F16 contains numerous Ef in L-1a, and therefore assumes trizonal or at least the propetrizonal appearance.L-5b-6 contain more and coarser fibres than F-15 but has significantly less fibers than F-14 unistriate, infraradiate (L-4= less intense than 5b)

Subregio typica
Characteristic is the appearance of very strong individual fibers in L-1c, which also occur in the normally very fiber-poor L-2 (lamina dysfibrosa).These so-called ultratangential fibers are typical in parts of the allocortex and at their transitions to the socortex [114,45].

Div.infraradiata
The division shows only very rudimentary radii in L-5a+4 and is very poor in fibers in the outer layers, especially in L-3b and 4.

Subdivisio quadrizonalis
Both fields are characterized by hardly recognizable individual fibers in L-3b-6.
In L-1 four layers are distinguished, L-1c, like L-2, is characterized by the presence of individual fibers.L-3 has extraordinarily few fibers.Also, Ef in layers 3b-5a are not be observed and L-4 and L-5a are barely visible due to the lack of horizontal fibers.
However, L-5b stands out more due to the occurrence of coarser horizontal fibers.6aα shows a decrease of fibers, whereas increasing numbers of fibers are present in 6bα.
The radii end at the boundary of L-5a and L-5b.
No Ef are observed in layers 3b-5a. (Continued) Myelo-map on standard atlas  III L-1 is more fibrous than in F21 and F25; slightly more fibrous than in F18.L-4 is much less fibrous than in F25.L-4-6 and radii are less developed than in F18 and F25.L-4-6 shows fewer fibers than in F16, the radii are somewhat weaker than in F21.Trizonal; appears like F19 and F22.In L-4-6 the radii are much weaker than in F27.
F24 represents a transition field to the parietal area, and therefore falls somewhat out of the structural plan of this group.

Subregio medioradiata
This subregion occupies the most dorsal part of the Gyrus limbicus.One finds an increase in the horizontal fibers in the 3rd and 4th layers, a clear separation of layers 4 and 5a, and more radii in L-4 and L-5a.

Div.medioradiata
Subdivisio quadrizonalis (γαα of Vogt, 1910) Compared to the Subdivisio subtrizonalis, this subdivision has fewer Gf throughout (with possibly some increase in sublayers 3a and 1a.Bizonal to very gradually trizonal L-1a+b is much brighter than in F37, therefore, L-4-6 appear with somewhat fewer and finer fibers, L-4 is smaller than in F37, but otherwise very similar to it.

25
Unistriate, fiber -rich category, euradiate, L-4 = L-5 37 A. aequostriata F37 contains somewhat more fibers and thicker Ef, L-4 and L-3b are of equal width and L-1a+b is much better delineated from L-1c as the Ef of 1a+b are much coarser.

38-39 Subregio propeastriata
The subregion exhibits generally more and thicker fibres with F38 showing somewhat fewer and thinner fibers and F39 thicker fibers.Low contrast between L-5a and L4.L-1c is at least twice as wide as L-1a+b.
Fields 38 to 43 differ from the adjacent parietal area in that in the latter, L-5b differs very clearly from L-6α in terms of fiber abundance.
A part of this field (39 I ) exhibits less Gf and thinner Ef .
Unistriate, fiber -rich category, euradiate, L-4 = L-5  Strasburger [41] distinguished F42a as a fronto-parietal transition area.In it, L-5b stands out more clearly from L-5a and 6α than in F42, but less clearly than in the subsequent parietal area.Otherwise it coincides with F42.

43
A. atypica F-43, hidden in most parts in the central sulcus (and exposed as a narrow strip only) has fewer fibers than F42, resulting in improving recognition of L-5a and L-6aα.The amount of fibers is, however, higher than in the adjacent parietal region.

R. PROPEUNISTRIATA Areae 44-50
In this region, L-5b is more fibrous and therefore more distinct from 6aα than in the Regio unistriata euradiata grossofibrosa.L-6aα contains more fibers than the sublayer 5a.

44
A. tenuifasciculata H68-ext F44 is somewhat less fibrous and contains thinner Ef than in the neighboring F38.The width of L-1a+b is about half of L-1c.

Subregio propeunistriata
This SR shows a relatively wide and fiber-poor L-5a and a significantly darker L-6aα. ) have fewer fibers than in F59.In L-4-5b significantly less fibers are noted than in F55a and F58.
Div.trizonalis L-5a can not be defined in any of the three fields.
F63 is very poor in Gf, so that the If predominate in L-4-5b.
F-64 shows a augmentation of the If.
F-65. further increase in the number of If as compared to F63 and F64. (Continued) Myelo-map on standard atlas  IX The first column shows the numbers of the myeloarchitectonic fields distinguished in the parietal (Fields 67-96) and insular (Fields 97-102) cortex.We differentiate between myeloarchitectonic "Fields" (F) and cytoarchitectonic "Areas" (A).The next three columns show the hierarchical order from Subregio to Area (Field).The next column indicates where drawings or photographs (Ph) of the myeloarchitectonic cortical structure can be found (Ba: Batsch [94]; Br: Brockhaus [103]; H69: Hopf [28]; H70:Hopf [29]; V11: Vogt [62]; VV: Vogt and Vogt [16]).The last column only provides rough information about the typical and differentiating features of the individual field.A list of abbreviations can be found at the end of this table.References can be found in the main text.aaßa) Areae grossofibrosae (Vogt, 1911) Three well-defined fields can be distinguished here in the oral-caudal direction; the most oral field L-5b is much richer in fibers, the middle L-4 and 5b are equally rich, in the most caudal F4 is somewhat richer than L-5b.propebistriate and aequodense αβ) Divisio subeucingulata L-2 is less distinct from L-1c and L-3a than in the parietal types described so far.

69
Also different from F7 due to much fewer Gf and Ef. A. subeucingulata (Vogt, 1911) 75 a small field that is not always easy to discriminate.F87 stands out from its environment due to its high fiber content and its unitostriate character.H70: conjunctostriate βε) Divisio propeastriata This divisions differs from the last two ones in that L-6aα is barely visible.The pattern comes close to the astriate type.In an oral region, L-5a is as dark as L-6aα.The propeastriate character is thus more pronounced here.In the caudal region, L-5a is brighter than L-6aα.This division is therefore more propeunistriate.

βεα) Subdivisio typica
The subdivision contains 2 fields: F88 differs from F71, 72 and 73 by its discingular character and much thinner individual fibers in L-4-6.F89 contains fewer Gf and much fewer and thinner Ef than F86.

88
A. dives 88a, 88p Ba; V11, F88 is the most oral and smallest area of the inferior parietal lobe.It extends to the parietal operculum and can be (Continued) XVI  J. K. Mai1 and M. Majtanik divided into the frontal F88a and the F88p, which is located somewhat above and on top of the operculum.
F88a has fewer fibers than F88p and slightly more fibers than the adjacent F73-3 in opercular direction.F88a is propeastriate.
F88p connects caudally to 88a and is generally richer in fibers.As the sublayers of the L-1 can be so well developed that one could speak of a quadrizonal type.
F88 is well distinguished from F72, 73 and 71 by its  In this field, too, a number of transition areas can be distinguished: to the intraparietal sulcus, to the temporal lobe and caudally to the occipital lobe (Batsch, 1956).
propeunistriate to propeastriate 2. Regio (prope-) supraradiata (Rose, 1935, p. 756) This region is characterized by a relatively large number of thick Ef in L-1 and a relatively large number of radial bundles and few horizontal fibers in L-3.It is divided into two sub-regions, from which eusfascial and a dysfascial section is distinguished in the caudo-oral part.

α) Subregio typica
Fields 91 to 93 scarcely come to the surface, while fields 94 to 96 occupy the surface of the cingulate gyrus and F94 can reach a quite considerable extent here.

(Continued)
Myelo-map on standard atlas  XVII The whole subregion is propesupraradiate (the fibers reach beyond L-3-3, partly into L-3-1).The proximity to the allocortex is evident by the distinctiveness of L-1.
αα) Div.eufasciata 91 A. eufasciata Ba, H60, H69; V11, F91 wraps around the end of the corpus callosum and borders on the retrosplenial region, which belongs to the allocortex and is not counted as part of the parietal area.F91 presents in L-1a+b, but also in L-1c, a great number of coarse Ef.It is a type dyscingulatus and conjunctus.L-5a is clearly lighter than L-4 and also L-5b ,due to the narrowing of the radii and decreasing numbers of Gf, as well as of Ef.On the other hand L-5a is such dark that the area must be described as subunitostriate.L-6aa is significantly brighter than L-5a.

Insula
Vogt and Vogt (1919)  The radii are medium wide and have thicker Ef, L-1a+b is very narrow and shows a much greater abundance of basic fibers than L-1c.The lamina dysfibrosa (L-2) is notable for its lack of fibers.
Otherwise it is a subconjunctostriate, externodenseior and externolatior cortex.
L-1c as wide as all previous strata.Dense fiber plexus.).This numbering system leaves no room for the occipital (A 18) and striatal (A17) subregions.We have therefore interposed numbers starting at 200.The list is followed by the (modified) table with the classification of the pre-occipital fields according to Lungwitz [40].A list of abbreviations can be found at the end of this supplement.References can be found in the main text.shows the lowest fiber density, while the most fibers can be found in the lateral subregion.
The entire temporopolar isocortex is characterized by its thickness, its lack of fibers and its singulostriate character.The fiber feltwork is intense only in the lamina tangentialis and in the outer stripe of Baillarger.Coarse Ef do not occur.As a result, no stripe of Kaes-Bechterew is noticeable.

Area
Subregio temporopolaris medialis tp.m H68.The medial subregion is separated from the laterally located fields by a deep sulcus which is constant in all brains.
Of the subregions of the temporal pole, the medial one (tp.m) is characterized by its broad cortex and a fiber density that is lower than in the other subregions.The only exception is L-1, which is emphasized here.The fiber content then gradually increases laterally toward tp.l, which has the greatest fiber abundance of all temporopolar fields.SUPPLEMENT 4: Isocortex Temporalis For our analysis of the cortex of the temporal isocortex we included the reports from Beck [80], Rose [113], particularly from Hopf [26,46,47] because those are the most detailed and recent studies and because results were at least in part confirmed by photometric analyses.
The first column shows the numbers of the distinguished myeloarchitectural fields for the temporal isocortex (fields 120-182).We differentiate between myeloarchitectonic characterized "fields" (F) and cytoarchitectonic characterized "areas" (A).The second to fourth columns separate subregions (SR) from divisions (Divisio, Div) and individual myeloarchitectural fields.The next column indicates where photos can be found that illustrates this field (H54: Hopf [46]; H68: Hopf [26].In the last column ("Hopf [46]") the distinguishing features of the individual fields are listed in brief.Hopf's classification system is presented in a table at the end of this supplement.
shows L-1 as bright subquadrizonal; L-2-6 show more Gf and in L-3-6 thinner Ef than in F3.It differs from the F3 because it has fewer fibers in L-1a, thicker Ef in the L-1b, and thinner ones in L-3-6.On the other hand, it has more basic Gf in layers 2-6bα slightly trizonal.This field generally exhibits fewer fibers with thinner Ef.The width of L-1a+b equals L-1c and contains a significant lesser amount of fibres, resulting in uncertain distinction.L-5a appears darker than in F47.Strasburger (1937) regarded Vogt's F45 and F46 as one common field.are (about 3/5 times) wider than L-1c.Ef are more delicate than in F44 and F45.

F89
can be broken down into a varying number of subfields(Batsch, 1956), but the subfields ventrally to the temporal lobe and dorsally to the intraparietal sulcus are quite constant.propeastriateβαβ) Subdivisio atypicaIn the only field of this subdivision, L-5a is slightly brighter than L-6aα.The F90 differs from the F85 and 86 in that it has fewer fibers in L-6, much thinner individual fibers and a stronger tenuifascial structure.most caudal field in the inferior parietal lobe; it does not extend beyond the intraparietal sulcus.It differs from F86 and F85 because of its lack of fibers in L-3-6, much thinner individual fibers and a stronger tenuifascial structure.

SUPPLEMENT 3 :
Isocortex OccipitalisThe first two column show the consecutive numbers of the parceling scheme proposed by Nieuwenhuys and Broere[22]  and the field names byLungwitz [40]  for the pre-occipital region (A 18).The next column indicates where to find figures characterizing the myeloarchitectonic cortical structure of each relevant field (EK: von Economo andKoskinas [63]; L=Lungwitz [40] [figure number]; VV:Vogt and Vogt [16] [figure number] tp.m.i is the most medial field of tp.It has a considerable extent and, with the exception of the caudolateral part, occupies the entire medial temporopolar gyrus.It borders caudolaterally the Formatio mesocorticalis temporalis (Brockhaus) of the Cortex claustralis and thus ends before the point at which the temporal lobe fuses at the temporal stem.si.p. rr tp.m.i is extremely fibrous.tp.m.e is a small field located on the medial temporopolar gyrus and essentially forms the medial lip of the medial temporopolar sulcus.si.p.rr L-1 is trizonal; L-4 and Rb are accentuated.clearly singulostriate (no stripe of Baillager recognizable)

3 .
Behavior of the fibers in individual layers and of the Ef (singular fibers): 1d = L-1 dives, (KB) = KB-stripe is weakly indicated, KB = KB-stripe is well recognized, KB = KBstripe is obvious.Ef = Ef clearly stand out in the overall picture of the area.4. Appearance of the radially aligned fiber bundles and fibers (Rb, Rf): r = Rb are moderately dense, rr = Rb are medium dense, rrr = Rb stand very tight.The thickness of the individual Rf increases at moderate density from r to rr to rrr; at medium density from 1r to 2r etc..
and M. Majtanik40-41Subregio unistriata degrediensIn this subregion the abundance and coarseness of fibers, the eufasciate character and the width of L-4 and L-1c are progressively decreasing.
* and very rich in fibers which is reflected by the dark appearance.L-1 3 are especially thin, and L-4-6 are especially wide.L-1a b is noticeably narrower than in F39, 38.L-4 and L-5b are almost astriate.L-4-6 has significantly more fibers than F39.
Subregio subunitostriataTrizonal.In this subregion L-5a shows less contrast.The Ef are coarser in character.
6. R. UNITOSTRIATA Areae 57-66Of the two SR the Subregio subunitostriata shows significantly fewer fibers in L-5a.(F56-66:Broca-Region; seeKreht, 1937a: cytoarchitecture).Trizonal.Very similar to F65, on average probably somewhat poorer in Ef (therefore brighter) than F65.L-5b has somewhat fewer fiber and is narrower than in F65.L-4 is significantly less developed than L-5b and thus weaker than L-4 in F65.F59a contains significantly more Ef in L-5a than F54a,b and F53, but fewer than L-5a in F58 and F59.L-4 is somewhat weaker than L-5b in F59a.unitostriate, euradiateDiv.multostriataL-3 is very rich in fibers, but in the upper part of L-3a there is even a special accumulation of stripes (including of Kaes-Bechterew).The most fibrous field of the whole inferior frontal gyrus (both horizontal stripes almost completely merged).Trizonal.L-1a+b are very rich in fibers with numerous relatively thick Ef.L-1c, 2 are rich in fibers but with only few Ef; L-2 is well defined.L-3-6 are highly fibrous; L-4 = 5b.L-5a contains only slightly fewer fibers than L-4, 5b, 6α.unitostriate, euradiateDiv.propeunistriataL-6aαcontains more fibers than all other divisions of the Subregio subunitostriata, thus heralding the transition to the neighboring unistriate type of the fields 5 and 9.resembles F62 with respect to structure and fiber content.Subquadrizonal; L-1 here has much less fibers than in F62.In L-2,3 hardly any Ef are noted.
(Braitenberg, 1956 p. 195)with strong radial fibers reaching into the upper layers of the cortex (up to L-1c).Trizonal.L-1a+b is very rich with respect to coarse Ef; even richer in this respect than F63.In L-1c numerous Ef that stand narrower than in F-65.L-4-5b forms a uniform band of the fibers.6αhardlyhas fewer fibers than L-4-5b.unitostriate,euradiateAnnotation:Hopf [40] could not define the fields 3,7,29,40,46 with certainty.Abbreviations: aequilatus=equilateral (with equal sides); B1=outer Baillarger stripe (Gennari stripe; IV.Lamina granularis); Subregio eucingulata .The most important distinguishing features relate first, to the changing abundance of medullary fibers and second, the length of the Rf as well as the number and ratio of theHf (Rose [113]).According to varying degrees of the eucingulate character this subregion can be divided into an eucingulate and a Divisio eucingulata The Subdivisio reuniens mediates the transition between the parietal isocortex and the frontal Isocortex.It can be distinguished from the caudal Subdivisio typica by is less sharply distintion of L-5b from L-6a.ααα) Subdivisio reuniensThe anterior slope of the posterior central gyrus is to be thought of folded up to the front.In this way, fields F67 and F69, which are otherwise hidden in the central furrow, are shown on the surface map.Only on the medial side do both fields reach the surface.Myelo-map on standard atlas  XI expressing the transitional character of this subarea to the bistriate fields is.H70: propeunistriate ααβ) Subdivisio typica The opercular section contains-like the Divisio reuniensthinner individual fibers than the more dorsal parts.Vogt distinguishes the tenuifibrose opercular fields (F72-74) from the parietal grossofibrose fields (F69-71).
Batsch[94]divided this field into four subareas, of which F67-1 is bistriate, aequodense and externolatior; F67-2 is bistriate and aequodense; F67-3 can be described as bistriate, externodensior and externolatior and F67-4 is bistriate, aequodense and externolatior.F68 is one of the most fibrous fields in the entire parietal area.At the lateral part it forms a transition to the field F72. and mixtoradiate.withonly slightly narrower L-5a, with many but relatively thin individual fibers in L-4-6.The two Baillarger stripes stand out somewhat more clearly(Continued) Myelo-map on standard atlas  XIII does not differ from L-1c with respect to the fiber content, i.e. the division is bizonal.It consists of two easily distinguishable fields.
unistriate ββ) Div.propeunistriata This division forms a transition area between the frontal isocortex and the parietal isocortex in the cingulate gyrus.It is already bistriate.L-5b, however, differs relatively little from L-6aα.It is also characterized by the fact that L-1a+b (Continued) propeunistrite and internodensiate ßγ) Div.bistriata Vogt divided the region into one field on the median side between the area formed by F76-78 together with the Regio propesupraradiata and the main section of the Divisio bistriata (therefore Subdivisio intermedia).It is then followed by the distinctly bistriate Subdivisio bistriata.This occupies the main part of the praecuneus and the dorsal part of the superior parietal lobule.ßγα) Subdivisio intermedia The intermediate character of this subdivision is revealed in the oral half by the fact that a narrow L-5aα is reminiscent of the propeunitostriate character of the adjoining Regio propesupraradiata, while a caudal half is decidedly bistriate.The oral half is less eu-and tenuifascial than the caudal .ßyββ) Areae subbistriatae An oral field with few fibers may be distinguished from a caudal field with more F81 is bistriate, pronounced eu-and tenuifascial.In L-1 and in L-4-6 numerous individual fibers stand out.It forms a transition to the adjacent fields.It is considerably more character and much thinner individual fibers F89 is more eufascial compared to F88 .It shows fewer Gf and, above all, much fewer and thinner Ef than F86.In a dorsal half, L-1a+b is somewhat wider and has fewer fibers.
Myelo-map on standard atlas  XXIX tp.m.p is a relatively small field that adjoins tp.m.e caudally and, like this, extends laterally to the base of the medial temporopolar sulcus.si.p.1d.rrL-1 is broad and quadrizonal and contains somewhat coarser Ef than tp.m.i.The field differs from tp.m.i and tp.m.e notably by the higher content in L-1 and a denser arrangement of the Rb.tp.m.p forms a transition zone between the isocortical tp and the mesocortical entorhinal area.tp.m.pt at the mediobasal edge of the tp borders the entorhinal region.It stands structurally between the isocortical tp.m.if and the Formatio mesocorticalis temporalis (Brockhaus).Supraradiary fibers -typical for allocortical areas -are missing.si.p. rr L-5a is lighter, L-5b somewhat darker, but an inner Baillarger stripe is not recognizable and this field is therefore classified as singulostriate.tp/mtm forms the caudal continuation of tp.m.i at the transition between the isocortical pole region to the Area mesocorticalis temporalis medialis.Compared to tp/mti, it has significantly fewer fibers.It differs from tp.m.i mainly by a darker L-1 and a wider but The inferior field extends from the temporal pole to the limen insulae.Its oral section lies mainly on the basal surface and only to a lesser extent on the lateral surface.Caudally this field becomes to lie in t2 so that it is no longer shown on the surface map.tp si. p. rr tp.m.if occupies the mediobasal area of the temporal pole between tp.v.if and tp.m.i.The caudal portion is partially covered by the beginning T4.The euradiary characteristic is only shown on intensely stained preparations..v.if has very few fibers in all layers.It differs from the medially following tp.m.if by a better developed L-4; on the other hand, the its L-1 is less well