Accessible Unlicensed Requires Authentication Published by De Gruyter November 30, 2021

Alcohol-Based Sanitizers: An Effective Means for Preventing the Spread of Contagious Viral Diseases Including COVID-19

Desinfektionsmittel auf Alkoholbasis: Ein wirksames Mittel zur Verhinderung der Ausbreitung ansteckender Viruskrankheiten einschließlich COVID-19
Narendra Kumar Chaudhary, Biswash Guragain, Summi Rai, Nabina Chaudhary, Rahul Chaudhary, KM Sachin, Reena Lamichhane-Khadka and Ajaya Bhattarai


The global community is struggling with the highly contagious COVID-19. Returning to \normal life" now poses risks, and the use of appropriate protective measures has become necessary to continue daily life and protect public health. The main protective measures to prevent transmission of COVID-19 are masks, soaps and disinfectants. Because coronavirus is a \lipid-enveloped virus", it is very sensitive to lipid-dissolving chemicals and can therefore be effectively removed by washing hands sufficiently with soap and water. However, using an alcohol-based disinfectant is a more viable option for outdoor use. Alcohol-based disinfectants are inexpensive, immediately effective, easy to use and better tolerated by the skin compared to other disinfectants. WHO recommends disinfectants containing 75% isopropanol or 80% ethanol as highly effective in inactivating the SARS-CoV-2-virus. The current review discusses the role of alcohol-based hand sanitizers (ABHS) in preventing the spread of viruses, their side effects on human health, and suggests the use of alcohol-based sanitizers as potentially effective in combating the current epidemic.


Die Weltgemeinschaft kämpft mit dem hochansteckenden COVID-19. Die Rückkehr zu einem ,,normalen Leben\ birgt nun Risiken, und die Anwendung geeigneter Schutzmaßnahmen ist notwendig geworden, um das tägliche Leben weiterzuführen und die öffentliche Gesundheit zu schützen. Die wichtigsten Schutzmaßnahmen zur Verhinderung der Übertragung von COVID-19 sind Masken, Seifen und Desinfektionsmittel. Da das Coronavirus ein ,,lipidumhülltes Virus\ ist, reagiert es sehr empfindlich auf lipidauflösende Chemikalien und kann daher durch ausreichendes Waschen der Hände mit Wasser und Seife effektiv entfernt werden. Die Verwendung eines Desinfektionsmittels auf Alkoholbasis ist jedoch eine praktikablere Option für den Einsatz im Freien. Desinfektionsmittel auf Alkoholbasis sind preiswert, sofort wirksam, einfach anzuwenden und werden im Vergleich zu anderen Desinfektionsmitteln besser von der Haut vertragen. Die WHO empfiehlt Desinfektionsmitteln mit 75% Isopropanol oder 80% Ethanol als hochwirksam bei der Inaktivierung des SARS-CoV-2-Virus. Die aktuelle Übersichtsarbeit diskutiert die Rolle von alkoholbasierten Händedesinfektionsmitteln bei der Verhinderung der Ausbreitung von Viren, ihre Nebenwirkungen auf die menschliche Gesundheit und schlägt die Verwendung von alkoholbasierten Desinfektionsmitteln als potenziell wirksam bei der Bekämpfung der aktuellen Epidemie vor.

Dr. Ajaya Bhattarai Department of Chemistry, M.M.A.M.C (Tribhuvan University) Biratnagar Nepal


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Received: 2020-09-28
Accepted: 2021-04-14
Published Online: 2021-11-30

© 2021 Walter de Gruyter GmbH, Berlin/Boston, Germany