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Licensed Unlicensed Requires Authentication Published by De Gruyter September 25, 2021

Weakening of the Transdermal Effect of p-Phenylenediamine Pigments by the Temperature-Sensitive Poloxamer Sodium Alginate Gel

Schwächung der transdermalen Wirkung von p-Phenylendiamin-Pigmenten durch das temperatursensitive Poloxamer-Natriumalginat-Gel
Haiyan Gao

Haiyan Gao: associate professor, she received a doctorate in science from the Institute of Coal Chemistry, Chinese Academy of Sciences in 2003. Research fields are physical chemistry, synthesis and application of chemicals School of Chemical and Material Engineering, Jiangnan University, Wuxi, Jiangsu, P.R. China

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, Yue Zhou

Yue Zhou: postgraduate School of Chemical and Material Engineering, Jiangnan University, Wuxi, Jiangsu, P.R. China

, Jianguo Wang

Jianguo Wang: postgraduate School of Chemical and Material Engineering, Jiangnan University, Wuxi, Jiangsu, P. R. China

and Hujun Xu

Hujun Xu: professor, he received his Ph. D. degree in 2005 from Nanjing University of Science and Technology, P. R. China. He has been involved in surfactants and detergents for over 30 years. He has published over 70 papers in the field of surfactants and detergents, School of Chemical and Material Engineering, Jiangnan University, Wuxi, Jiangsu, P. R. China

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Abstract

A temperature-sensitive hair dye was prepared with a poloxamer-sodium alginate mixture. When the hair dye was applied to the hair (< 32 °C), it retained its flow dynamics. The hair dye was able to undergo a phase change and formed a solid as soon as it touched the scalp (32°C), which reduced the transdermal amount of p-phenylenediamine (PPD) and also adverse effects and toxicity. Compared to a conventional hair dye, the temperature-sensitive hair dye achieved a reduction of the transdermal amount of p-phenylenediamine by almost 65% at different concentrations. At the same time, the colouring effect was not significantly reduced. The poloxamer alginate hydrogel can be used as a novel colouring material to reduce the harm of the dye intermediate to the human body when colouring hair.

Zusammenfassung

Es wurde ein temperaturempfindliches Haarfärbemittel mit einer Poloxamer-Natriumalginat-Mischung hergestellt. Beim Auftragen des Haarfarbstoffs auf das Haar (< 32°C), behielt er seine Fließdynamik. Der Haarfarbstoff war in der Lage, einen Phasenwechsel zu vollziehen und bildete einen Feststoff, sobald er die Kopfhaut (32°C) berührte, was die transdermale Menge an p-Phenylendiamin (PPD) reduzierte und die Nebenwirkungen und Toxizität verringerten. Im Vergleich zu einem konventionellen Haarfärbemittel reduzierte das temperaturempfindliche Haarfärbemittel die transdermale Menge an p-Phenylendiamin bei verschiedenen Konzentrationen um fast 65%. Gleichzeitig wurde die Färbewirkung nicht signifikant reduziert. Das Poloxamer-Alginat-Hydrogel kann als neuartiges Färbematerial verwendet werden, um den Schaden des Farbstoff-Zwischenprodukts für den menschlichen Körper beim Färben der Haare zu reduzieren.


Mrs. Haiyan Gao School of Chemical and Material Engineering Jiangnan University Wuxi Jiangsu P. R. China Telephone: +86 13382888939
Prof. Dr. Hujun Xu School of Chemical & Material Engineering Jiangnan University Wuxi China E-mail:

About the authors

Mrs. Haiyan Gao

Haiyan Gao: associate professor, she received a doctorate in science from the Institute of Coal Chemistry, Chinese Academy of Sciences in 2003. Research fields are physical chemistry, synthesis and application of chemicals School of Chemical and Material Engineering, Jiangnan University, Wuxi, Jiangsu, P.R. China

Yue Zhou

Yue Zhou: postgraduate School of Chemical and Material Engineering, Jiangnan University, Wuxi, Jiangsu, P.R. China

Jianguo Wang

Jianguo Wang: postgraduate School of Chemical and Material Engineering, Jiangnan University, Wuxi, Jiangsu, P. R. China

Prof. Dr. Hujun Xu

Hujun Xu: professor, he received his Ph. D. degree in 2005 from Nanjing University of Science and Technology, P. R. China. He has been involved in surfactants and detergents for over 30 years. He has published over 70 papers in the field of surfactants and detergents, School of Chemical and Material Engineering, Jiangnan University, Wuxi, Jiangsu, P. R. China

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Received: 2020-12-11
Accepted: 2021-04-14
Published Online: 2021-09-25
Published in Print: 2021-09-30

© 2021 Walter de Gruyter GmbH, Berlin/Boston, Germany

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