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Licensed Unlicensed Requires Authentication Published by De Gruyter May 19, 2022

Extracted saponin from Anabasis setifera plant as a biosurfactant for stabilization of oil in water (O/W) nano-emulsion based on date palm (Phoenix dactylifera) kernel oil

Fatemeh Rigi

Abstract

Saponin was extracted from the Anabasis setifera plant and used to stabilize an oil-in-water (O/W) emulsion based on date palm kernel oil. Different amounts of the extracted saponin were used with a constant oil concentration (1.5% w/w). The droplet size distribution, emulsion droplet size value (d-ave), polydispersity index (PDI) and zeta potential of the emulsions were determined using dynamic light scattering (DLS). These parameters were measured and compared after seven days of emulsion preparation. The best results (d-ave = 41.7 nm, PDI = 0.1 and zeta potential = −29.8 mV) were obtained for the CMC of saponin. Both the oil and the surfactant were specifically extracted and used from the nature of Saravan in the Baluchestan region of Iran. This research presents a green and cost-effective aspect for potential formulations of nano-emulsions that can be used in the food and cosmetic industries.


Corresponding author: Fatemeh Rigi, Department of Production and Utilization of Medicinal Plants, Faculty of Agriculture, Higher Education Complex of Saravan, Saravan, Iran, E-mail:

Funding source: Research Management of Higher Education Complex of Saravan

Award Identifier / Grant number: 2856

  1. Author contributions: All the authors have accepted responsibility for the entire content of this submitted manuscript and approved submission.

  2. Research funding: This work was supported by the Higher Education Complex of Saravan with project number 2856.

  3. Conflict of interest statement: The authors declare no conflicts of interest regarding this article.

References

1. Goodarzi, F., Zendehboudi, S. A comprehensive review on emulsions and emulsion stability in chemical and energy industries. Can. J. Chem. Eng. 2019, 97, 281–309; https://doi.org/10.1002/cjce.23336.Search in Google Scholar

2. Gupta, A., Eral, H. B., Hatton, T. A., Doyle, P. S. Nano-emulsions: formation, properties and applications. Soft Matter 2016, 12, 2826–2841; https://doi.org/10.1039/C5SM02958A.Search in Google Scholar

3. Mcclements, D. J. Nano-emulsions versus microemulsions: terminology, differences, and similarities. Soft Matter 2012, 8, 1719–1729; https://doi.org/10.1039/C2SM06903B.Search in Google Scholar

4. Valentim, D. S. S., Duarte, J. L., Oliveira, A. E. M. F. M., Cruz, R. A. S., Carvalho, J. C. T., Conceição, E. C., Fernandes, C. P., Tavares-Dias, M. Nano-emulsion from essential oil of pterodon emarginatus (fabaceae) shows in vitro efficacy against monogeneans of colossoma macropomum (pisces: serrasalmidae). J. Fish. Dis. 2018, 41, 443–449; https://doi.org/10.1111/jfd.12739.Search in Google Scholar PubMed

5. Lôbo De Souza, M., Dourado, D., Pinheiro Lôbo, I., Couto Pires, V., Nunes De Oliveira Araújo, S., De Souza Rebouças, J., Costa, A. M., Pinho Fernandes, C., Machado Tavares, N., De Paula Pereira, N., Rocha Formiga, F. Wild passiflora (passiflora spp.) seed oils and their nano-emulsions induce proliferation in hacat keratinocytes cells. J. Drug Deliv. Sci. Technol. 2022, 67, 102803–102814; https://doi.org/10.1016/j.jddst.2021.102803.Search in Google Scholar

6. Che Marzuki, N. H., Wahab, R. A., Abdul Hamid, M. An overview of nano-emulsion: concepts of development and cosmeceutical applications. Biotechnol. Biotechnol. Equip. 2019, 33, 779–797; https://doi.org/10.1080/13102818.2019.1620124.Search in Google Scholar

7. Dasgupta, N., Ranjan, S., Gandhi, M. Nano-emulsions in food: market demand. Environ. Chem. Lett. 2019, 17, 1003–1009; https://doi.org/10.1007/s10311–019–00856–2.10.1007/s10311-019-00856-2Search in Google Scholar

8. Gianella, A., Jarzyna, P. A., Mani, V., Ramachandran, S., Calcagno, C., Tang, J., Kann, B., Dijk, W. J. R., Thijssen, V. L., Griffioen, A. W., Storm, G., Fayad, Z. A., Mulder, W. J. M. Multifunctional nano-emulsion platform for imaging guided therapy evaluated in experimental cancer. ACS Nano 2011, 5, 4422–4433; https://doi.org/10.1021/nn103336a.Search in Google Scholar PubMed PubMed Central

9. Ferreira, G. A. Geometric features in lyotropic liquid crystalline phase transitions observed in aqueous surfactant systems. J. Dispers. Sci. Technol. 2021, https://doi.org/10.1080/01932691.2021.1924192.Search in Google Scholar

10. Liao, Y., Li, Z., Zhou, Q., Sheng, M., Qu, Q., Shi, Y., Yang, J., Lv, L., Dai, X., Shi, X. Saponin surfactants used in drug delivery systems: a new application for natural medicine components. Int. J. Pharm. 2021, 603, 120709–120722; https://doi.org/10.1016/j.ijpharm.2021.120709.Search in Google Scholar PubMed

11. Güçlü-Üstündağ, Ö., Mazza, G. Saponins: properties, applications and processing. Crit. Rev. Food Sci. Nutr. 2007, 47, 231–258; https://doi.org/10.1080/10408390600698197.Search in Google Scholar PubMed

12. Jarzębski, M., Siejak, P., Smułek, W., Fathordoobady, F., Guo, Y., Pawlicz, J., Trzeciak, T., Kowalczewski, P. Ł., Kitts, D. D., Singh, A., Pratap Singh, A. Plant extracts containing saponins affects the stability and biological activity of hempseed oil emulsion system. Molecules 2020, 25, 2696–2711; https://doi.org/10.3390/molecules25112696.Search in Google Scholar PubMed PubMed Central

13. Salminen, H., Bischoff, S., Weiss, J. Formation and stability of emulsions stabilized by Quillaja saponin–egg lecithin mixtures. J. Food Sci. 2020, 85, 1213–1222; https://doi.org/10.1111/1750–3841.15104.10.1111/1750-3841.15104Search in Google Scholar PubMed

14. Yang, Y., Leser, M. E., Sher, A. A., Mcclements, D. J. Formation and stability of emulsions using a natural small molecule surfactant: quillaja saponin (q–naturale®). Food Hydrocolloids 2013, 30, 589–596; https://doi.org/10.1016/j.foodhyd.2012.08.008.Search in Google Scholar

15. Ralla, T., Salminen, H., Tuosto, J., Weiss, J. Formation and stability of emulsions stabilised by yucca saponin extract. Int. J. Food Sci. Technol. 2018, 53, 1381–1388; https://doi.org/10.1111/ijfs.13715.Search in Google Scholar

16. Zhu, Z., Wen, Y., Yi, J., Cao, Y., Liu, F., Mcclements, D. J. Comparison of natural and synthetic surfactants at forming and stabilizing nano-emulsions: tea saponin, quillaja saponin, and tween 80. J. Colloid Interface Sci. 2019, 536, 80–87; https://doi.org/10.1016/j.jcis.2018.10.024.Search in Google Scholar PubMed

17. Mohammadi, M., Alaei, M., Bajalan, I. Phytochemical screening, total phenolic and flavonoid contents and antioxidant activity of anabasis setifera and salsola tomentosa extracted with different extraction methods and solvents, orient. Pharm. Exp. Med . 2016, 16, 31–35; https://doi.org/10.1007/s13596–016–0220–3.10.1007/s13596-016-0220-3Search in Google Scholar

18. Abdou, A. M., Abdallah, H. M., Mohamed, M. A., Fawzy, G. A., Abdel-Naim, A. B. A new anti–inflammatory triterpene saponin isolated from anabasis setifera. Arch. Pharmacal. Res. 2013, 36, 715–722; https://doi.org/10.1007/s12272–013–0075–9.10.1007/s12272-013-0075-9Search in Google Scholar PubMed

19. Nowrouzi, I., Mohammadi, A. H., Khaksar Manshad, A. Double–chain single–head modification of extracted saponin from anabasis setifera plant and its effects on chemical enhanced oil recovery process by surfactant–alkali slug injection into carbonate oil reservoirs. J. Petrol. Sci. Eng. 2021, 201, 108438–108447; https://doi.org/10.1016/j.petrol.2021.108438.Search in Google Scholar

20. Nowrouzi, I., Mohammadi, A. H., Manshad, A. K. Water–oil interfacial tension (ift) reduction and wettability alteration in surfactant flooding process using extracted saponin from anabasis setifera plant. J. Petrol. Sci. Eng. 2020, 189, 106901–106910; https://doi.org/10.1016/j.petrol.2019.106901.Search in Google Scholar

21. Atghaei, M., Sefidkon, F., Darini, A., Sadeghzadeh Hemayati, S., Abdossi, V. Essential oil content and composition of the spathe in some date palm (phoenix dactylifera l.) varieties in Iran. J. Essent. Oil–Bear. Plants 2020, 23, 292–300; https://doi.org/10.1080/0972060X.2020.1743768.Search in Google Scholar

22. Hekmatnia, M., Hosseini, S. M., Safdari, M. Water use assessment of date in Sistan and Baluchestan province based on the concept of virtual water, Iran. J. Soil. Water. Res. 2020, 51, 513–524; https://doi.org/10.22059/ijswr.2019.289422.668322.Search in Google Scholar

23. Karizaki, V. M. Iranian dates and ethnic date–based products. J. Ethnic. Foods. 2017, 4, 204–209; https://doi.org/10.1016/j.jef.2017.08.002.Search in Google Scholar

24. Mrabet, A., Jiménez-Araujo, A., Guillén-Bejarano, R., Rodríguez-Arcos, R., Sindic, M. Date seeds: a promising source of oil with functional properties. Foods 2020, 9, 787–800; https://doi.org/10.3390/foods9060787.Search in Google Scholar PubMed PubMed Central

25. Hamza, H., Elfalleh, W., Nagaz, K. Date palm seed oil (phoenix dactylifera l.) green extraction: physicochemical properties, antioxidant activities, and phenolic and fatty acid profiles. J. Food Qual. 2021, 2021, 2394220–2394228; https://doi.org/10.1155/2021/2394220.Search in Google Scholar

26. Maqsood, S., Adiamo, O., Ahmad, M., Mudgil, P. Bioactive compounds from date fruit and seed as potential nutraceutical and functional food ingredients. Food Chem. 2020, 308, 125522–125576; https://doi.org/10.1016/j.foodchem.2019.125522.Search in Google Scholar PubMed

27. Nehdi, I., Omri, S., Khalil, M. I., Al-Resayes, S. I. Characteristics and chemical composition of date palm (phoenix canariensis) seeds and seed oil. Ind. Crop. Prod. 2010, 32, 360–365; https://doi.org/10.1016/j.indcrop.2010.05.016.Search in Google Scholar

28. Jadhav, A. J., Holkar, C. R., Goswami, A. D., Pandit, A. B., Pinjari, D. V. Acoustic cavitation as a novel approach for extraction of oil from waste date seeds. ACS Sustain. Chem. Eng. 2016, 4, 4256–4263; https://doi.org/10.1021/acssuschemeng.6b00753.Search in Google Scholar

29. Ali, M. A., Al-Hattab, T. A., Al-Hydary, I. A. Extraction of date palm seed oil (phoenix dactylifera) by soxhlet apparatus. Int. J. Adv. Eng. Sci. Technol. 2015, 8, 261–271.Search in Google Scholar

30. Wang, C., Chao, Z., Sun, W., Wu, X., Ito, Y. Isolation of five glycosides from the barks of ilex rotunda by high-speed counter-current chromatography. J. Liq. Chromatogr. Relat. Technol. 2014, 37, 2363–2376; https://doi.org/10.1080/10826076.2013.832297.Search in Google Scholar PubMed PubMed Central

31. Canto, G. S. D., Treter, J., Yang, S., Borré, G. L., Peixoto, M. P. G., Ortega, G. G. Evaluation of foam properties of saponin from ilex paraguariensis a. St. Hil. (aquifoliaceae) fruits. Braz. J. Pharm. Sci. 2010, 46, 237–243; https://doi.org/10.1590/S1984–82502010000200010.10.1590/S1984-82502010000200010Search in Google Scholar

32. Ribeiro, B. D., Alviano, D. S., Barreto, D. W., Coelho, M. A. Z. Functional properties of saponins from sisal (agave sisalana) and juá (ziziphus joazeiro): critical micellar concentration, antioxidant and antimicrobial activities. Colloids Surf. A Physicochem. Eng. Asp. 2013, 436, 736–743; https://doi.org/10.1016/j.colsurfa.2013.08.007.Search in Google Scholar

33. Decroos, K., Vincken, J.-P., Van Koningsveld, G. A., Gruppen, H., Verstraete, W. Preparative chromatographic purification and surfactant properties of individual soyasaponins from soy hypocotyls. Food Chem. 2007, 101, 324–333; https://doi.org/10.1016/j.foodchem.2006.01.041.Search in Google Scholar

34. Benichou, A., Aserin, A., Garti, N. Steroid–saponins from fenugreek seeds: extraction, purification and surface properties. J. Dispersion Sci. Technol. 1999, 20, 581–605; https://doi.org/10.1080/01932699908943809.Search in Google Scholar

35. Tmáková, L., Sekretár, S., Schmidt, Š. Plant–derived surfactants as an alternative to synthetic surfactants: surface and antioxidant activities. Chem. Pap. 2016, 70, 188–196; https://doi.org/10.1515/chempap–2015–0200.10.1515/chempap-2015-0200Search in Google Scholar

36. Rai, S., Acharya-Siwakoti, E., Kafle, A., Devkota, H. P., Bhattarai, A. Plant–derived saponins: a review of their surfactant properties and applications. Sci 2021, 3, 44–62; https://doi.org/10.3390/sci3040044.Search in Google Scholar

37. Alvarado, V., Wang, X., Moradi, M. Stability proxies for water–in–oil emulsions and implications in aqueous–based enhanced oil recovery. Energies 2011, 4, 1058–1086; https://doi.org/10.3390/en4071058.Search in Google Scholar

Received: 2021-12-20
Accepted: 2022-02-15
Published Online: 2022-05-19
Published in Print: 2022-07-26

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