Synthesis of N-(2-Phenyl-cyclopropyI)-Substituted Nucleoside Analogues

René Csuk; Yvonne von Scholz

doi:10.1515/znb-1997-1116

Published by De Gruyter June 2, 2014

Synthesis of N-(2-Phenyl-cyclopropyI)-Substituted Nucleoside Analogues

René Csuk and Yvonne von Scholz

From the journal Zeitschrift für Naturforschung B

https://doi.org/10.1515/znb-1997-1116

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Abstract

A novel class of nucleoside analogues containing adenine, hypoxanthine, thymine, uracil, thiouracil and cytosine as the heterocyclic moieties have been prepared starting from 2-phenylcyclopropylamine. These compounds showed weak antitumor activity. The resolution of the racemates on an analytical scale was performed by HPLC using chiral phases.

: Nucleoside Analogues; HPLC

Received: 1997-9-3

Published Online: 2014-6-2

Published in Print: 1997-11-1

Synthesis of N-(2-Phenyl-cyclopropyI)-Substituted Nucleoside Analogues

Abstract

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