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Licensed Unlicensed Requires Authentication Published by De Gruyter June 2, 2014

Syntheses of Anomeric Pairs of New C-Nucleosides via 1,3-Dipolar Cycloaddition Reaction, Part I

  • Zahida Maqbool , Mashooda Hasan , Kevin T. Pott , Abdul Malik , Tanveer Ahmad Nizami and Wolfgang Voelter


A convenient pathway to a variety of β-and α-C-nucleosides has been developed by utilizing 1,3-dipolar cycloaddition reactions of various exocyclic and endocyclic heterocyclic ylides with β (5a) and α (5b) anomers of ethyl 3-(2′,3′-O-isopropylidene-5′-O-trityl-D-ribofurano-syl) propiolate, respectively. Assignment of configuration at exposition of the C-nucleosides could be made by a comparative study of the properties of corresponding α and β anomers with a reasonable degree of certainity.

Received: 1997-7-21
Published Online: 2014-6-2
Published in Print: 1997-11-1

© 1946 – 2014: Verlag der Zeitschrift für Naturforschung

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