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Abstract
A convenient pathway to a variety of β-and α-C-nucleosides has been developed by utilizing 1,3-dipolar cycloaddition reactions of various exocyclic and endocyclic heterocyclic ylides with β (5a) and α (5b) anomers of ethyl 3-(2′,3′-O-isopropylidene-5′-O-trityl-D-ribofurano-syl) propiolate, respectively. Assignment of configuration at exposition of the C-nucleosides could be made by a comparative study of the properties of corresponding α and β anomers with a reasonable degree of certainity.
Received: 1997-7-21
Published Online: 2014-6-2
Published in Print: 1997-11-1
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