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Licensed Unlicensed Requires Authentication Published by De Gruyter June 2, 2014

Isolation and Characterization of 1-Tigloyl-3-acetylazadirachtol from the Seed Kernels of the Thai Neem Azadirachta siamensis Valeton

  • H.-O. Kalinowski , C. Krack , K. Ermel and C. Chriathamjaree


The Thai neem A. siamensis (Valeton) is the main source for botanical insecticides in Thailand. Although azadirachtin A (aza A) is present in Thai neem, there are some other related compounds which may contribute to its bioefficiency. Analytical HPLC of Thai neem samples showed a peak closely eluted with azadirachtin. A large-scale cleanup involving two liquid/liquid extraction steps, silica filtration, and finally two successive preparative HPLC separations, resulted in the pure compound, which was identified as 1-tigloyl-3-acetylazadirachtol by 1D -and 2D -1H and 13C NMR spectroscopy.

Received: 1997-8-4
Published Online: 2014-6-2
Published in Print: 1997-11-1

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