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BY-NC-ND 3.0 license Open Access Published by De Gruyter June 2, 2014

Gold Nanoparticles Bearing an α-Lipoic Acid-based Ligand Shell: Synthesis, Model Complexes and Studies Concerning Phosphorescent Platinum(II)-Functionalisation

Ulrich Siemeling, Frauke Bretthauer, Clemens Bruhn, Tim-Patrick Fellinger, Wah-Leung Tong and Michael C.W. Chan

The surface functionalisation of gold nanoparticles (GNPs) with luminescent platinum complexes has been investigated, utilising α-lipoic acid derivatives for GNP stabilisation. Model complexes have been studied to mimic the chemisorption chemistry required to afford GNPs protected by an α-lipoic acid-based ligand shell with terminal functionalisation suitable for metal coordination, and the unambiguous binding of the cyclic disulfide moiety at a zero-valent precious metal core through oxidative addition has been confirmed by X-ray crystallography. Subsequently, gold nanoparticles bearing the α-lipoic acid-based ligand shell have been prepared and characterised, and a synthetic methodology for the immobilisation of PtII luminophores onto their surface has been established.

Graphical Abstract

 Gold Nanoparticles Bearing an α-Lipoic Acid-based Ligand Shell: Synthesis, Model Complexes and Studies Concerning Phosphorescent Platinum(II)-Functionalisation

Gold Nanoparticles Bearing an α-Lipoic Acid-based Ligand Shell: Synthesis, Model Complexes and Studies Concerning Phosphorescent Platinum(II)-Functionalisation

Received: 2010-3-31
Published Online: 2014-6-2
Published in Print: 2010-9-1

© 1946 – 2014: Verlag der Zeitschrift für Naturforschung

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 3.0 License.

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