Two Xanthones from Polygala paniculata and Confirmation of the 1-Hydroxy- 2,3,5-trimethoxy-xanthone at Trace Level by HRGC-MS:

Rodrigo Cristiano; Moacir G. Pizzolatti; Franco Delle Monache; Claudia M. Rezende; Alexsandro Branco

doi:10.1515/znc-2003-7-808

Open Access Published by De Gruyter June 2, 2014

Two Xanthones from Polygala paniculata and Confirmation of the 1-Hydroxy- 2,3,5-trimethoxy-xanthone at Trace Level by HRGC-MS

Rodrigo Cristiano , Moacir G. Pizzolatti , Franco Delle Monache , Claudia M. Rezende and Alexsandro Branco

From the journal Zeitschrift für Naturforschung C

https://doi.org/10.1515/znc-2003-7-808

Abstract

Polygala paniculata L. yielded the xanthones 1-hydroxy-5-methoxy-2,3-methylenedioxyxanthone (1) and 1,5-dihydroxy-2,3-dimethoxyxanthone (2), together with coumarin murragatin and flavonol rutin. Their structures were established by chemical and spectroscopic methods (EIMS, IR, ¹H and ¹³C NMR, NOE difference spectroscopy). By posterior analysis of an apolar crude extract using high resolution gas chromatography coupled to mass spectrometry (HRGC-MS) it was possible to characterize two sterol (spinasterol and Δ²⁵-spinasterol) and the minor 1-hydroxy-2,3,5-trimethoxyxanthone (3). Thus, the xanthone 3 was confirmed through of co-injection HRGC-MS of the respective extract with a certified standard obtained by methylation of 2 with diazomethane.

Keywords : Polygala paniculata; Xanthones; HRGC-MS

Received: 2002-12-30

Revised: 2003-3-1

Published Online: 2014-6-2

Published in Print: 2003-8-1

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 3.0 License.

Two Xanthones from Polygala paniculata and Confirmation of the 1-Hydroxy- 2,3,5-trimethoxy-xanthone at Trace Level by HRGC-MS

Abstract

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