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BY-NC-ND 3.0 license Open Access Published by De Gruyter June 2, 2014

New Steroidal Saponins from Rhizomes of Costus spiralis

  • Bernadete P. da Silva and José P. Parente EMAIL logo

Two new steroidal saponins were isolated from the rhizomes of Costus spiralis Rosc. Their structures were established as (3β,25R)-26-(β-ᴅ-glucopyranosyloxy)-22-hydroxyfurost-5- en-3-ylO-d-apio-β-ᴅ-furanosyl-(1→2)-O-[α-ʟ-rhamnopyranosyl-(1→4)]-β-ᴅ-glucopyranoside (1) and (3β,25R)-26-(β-ᴅ-glucopyranosyloxy)-22-hydroxyfurost-5-en-3-yl O-ᴅ-apio-β-ᴅ-furanosyl-( 154)-O-[α-ʟ-rhamnopyranosyl-(1→2)]-β-ᴅ-glucopyranoside (2). Their structural identifications were performed using detailed analyses of 1H and 13C NMR spectra including 2D NMR spectroscopic techniques (DEPT, COSY, HETCOR and COLOC) and chemical conversions. The steroidal saponins were evaluated for anti-inflammatory activity.

Received: 2003-5-21
Published Online: 2014-6-2
Published in Print: 2004-2-1

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