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BY-NC-ND 3.0 license Open Access Published by De Gruyter June 2, 2014

1,4-Benzoxazin-3-one, 2-Benzoxazolinone and Gallic Acid from Calceolaria thyrsiflora Graham and their Antibacterial Activity

Héctor R. Bravo, Sylvia V. Copaja, Sebastián Figueroa-Duarte, Madeleine Lamborot and José San Martín

Secondary metabolites, DIBOA, HBOA, 7-OH-HBOA, BOA and gallic acid, were isolated and quantified from Calceolaria thyrsiflora Graham, a native medicinal plant of Chile belonging to the Scrophulariaceae family. The highest DIBOA contents were determined in leaves (145 mmol kg-1 dry wt) and flowers (161 mmol kg-1 dry wt). Antibacterial activities of DIBOA, HBOA, BOA, gallic acid and infusions of flowers and leaves were determined. The phytomedicinal properties attributed to C. thyrsiflora Graham could be understood on the basis of its antibacterial activity

Received: 2004-11-18
Revised: 2005-1-5
Published Online: 2014-6-2
Published in Print: 2005-6-1

© 1946 – 2014: Verlag der Zeitschrift für Naturforschung

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 3.0 License.

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