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BY-NC-ND 3.0 license Open Access Published by De Gruyter June 2, 2014

Functional Properties of Dioscorin, a Soluble Viscous Protein from Japanese Yam (Dioscorea opposita Thunb.) Tuber Mucilage Tororo

  • Takeshi Nagai EMAIL logo and Toshio Nagashima


A soluble viscous protein was purified from yam (Dioscorea opposita Thunb.) tuber mucilage tororo by chromatographic steps, and its functional properties were estimated. The purified dioscorin having the molecular weight of about 200 kDa exhibited high scavenging activities against hydroxyl radicals (IC50 = 195.1 μg/ml) and superoxide anion radicals (IC50 = 92.7 μg/ml). Moreover, it showed extremely high angiotensin I-converting enzyme inhibitory activity (IC50 = 41.1 μg/ml). The results suggested that yam D. opposita tuber has a wide spectrum of strong antioxidative and antihypertensive activities and it could be utilized as a source of natural antioxidant.

Published Online: 2014-6-2
Published in Print: 2006-12-1

© 1946 – 2014: Verlag der Zeitschrift für Naturforschung

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 3.0 License.

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