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BY-NC-ND 3.0 license Open Access Published by De Gruyter June 2, 2014

Two New 11(15→1)Abeotaxanes with a 2,20-Epoxy Ring from the Needles of Taxus canadensis

  • Man-Li Zhang , Jing Zhang , Mei Dong , Shu-Hua Feng , Chang-Hong Huo , Françoise Sauriol , Qing-Wen Shi EMAIL logo , Yu-Cheng Gu , Hiromasa Kiyota and Bin Cong


Two 11(15→1)abeotaxanes having a tetrahydrofuran ring along the carbon atoms C-2, C-3, C-4, C-20 were identified for the first time from the needles of the Canadian yew, Taxus canadensis. The compounds could be identified as 4α,10β,13α-triacetoxy-15-benzoyloxy-2α,20β- epoxy-11(15→1)abeotax-11-ene-5α,7β,9α-triol () and 4α,7β,9α,10β,15-pentaacetoxy-2α,20β- epoxy-11(15→1)abeotax-11-ene-5α,13α-diol (2) on the basis of 1D-, 2D-NMR evidence and high-resolution FABMS analysis. Compound 1 showed weak growth inhibitory activities against T-98 and MM1-CB cells in vitro.

Received: 2008-5-13
Revised: 2008-7-28
Published Online: 2014-6-2
Published in Print: 2009-6-1

© 1946 – 2014: Verlag der Zeitschrift für Naturforschung

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 3.0 License.

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