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Licensed Unlicensed Requires Authentication Published by De Gruyter December 8, 2018

Analysis of the GC-MS of volatile compounds and the phytochemical profile and antioxidant activities of some Bulgarian medicinal plants

Dasha Mihaylova ORCID logo EMAIL logo , Radka Vrancheva , Ivelina Desseva , Ivan Ivanov ORCID logo , Ivayla Dincheva , Mariya Popova and Aneta Popova


The study’s objective was to investigate the volatile compounds, assess the total phenolic content and phenolic acids profile, determine the antioxidant capacity and evaluate the anthocyanin and flavonoid contents in stinging nettle (Urtica dioica L.), tansy (Tanacetum vulgare L.), bladder campion (Silene vulgaris (Moench) Garcke) and rosehip fruit (Rosa canina L. cv. Plovdiv 1). The total phenolic content ranged from 0.55±0.00 to 47.39±0.41 mg GAE/g dw, total flavonoids ranged from 0.45±0.02 to 17.27±0.45 mg QЕ/g dw and the total anthocyanins ranged from 0.94±0.23 to 58.11±2.85 mg/L. The results demonstrated that the selected research plants show auspiciously useful properties in fields like pharmacy, food preparation, cosmetics, etc. Furthermore, the most promising extraction methods in terms of bioactivity are decoction and tincture (U. dioica; T. vulgare; S. vulgaris) and tincture (R. canina). The current study could be regarded as a first detailed investigation of the biological activity and phytochemical composition of R. canina L. cv. Plovdiv 1.


This work was supported by the Ministry of Education and Science (Grant agreement №. DM 07/2).


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Received: 2018-08-09
Revised: 2018-11-03
Accepted: 2018-11-16
Published Online: 2018-12-08
Published in Print: 2018-12-19

©2019 Walter de Gruyter GmbH, Berlin/Boston

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