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Licensed Unlicensed Requires Authentication Published by De Gruyter December 7, 2021

An update on the progress of microbial biotransformation of commercial monoterpenes

  • Ruchika Mittal , Gauri Srivastava and Deepak Ganjewala ORCID logo EMAIL logo

Abstract

Monoterpenes, a class of isoprenoid compounds, are extensively used in flavor, fragrance, perfumery, and cosmetics. They display many astonishing bioactive properties of biological and pharmacological significance. All monoterpenes are derived from universal precursor geranyl diphosphate. The demand for new monoterpenoids has been increasing in flavor, fragrances, perfumery, and pharmaceuticals. Chemical methods, which are harmful for human and the environment, synthesize most of these products. Over the years, researchers have developed alternative methods for the production of newer monoterpenoids. Microbial biotransformation is one of them, which relied on microbes and their enzymes. It has produced many new desirable commercially important monoterpenoids. A growing number of reports reflect an ever-expanding scope of microbial biotransformation in food and aroma industries. Simultaneously, our knowledge of the enzymology of monoterpene biosynthetic pathways has been increasing, which facilitated the biotransformation of monoterpenes. In this article, we have covered the progress made on microbial biotransformation of commercial monoterpenes with a brief introduction to their biosynthesis. We have collected several reports from authentic web sources, including Google Scholar, Pubmed, Web of Science, and Scopus published in the past few years to extract information on the topic.


Corresponding author: Deepak Ganjewala, Amity Institute of Biotechnology, Amity University Uttar Pradesh, Sector-125, Noida 201303, UP, India, E-mail:

Acknowledgments

The corresponding author of the manuscript would like to thank Council of Scientific and Industrial Research (CSIR) New Delhi Government of India for providing financial support for our ongoing research program on microbial biotransformation of alkaloids. Also, I would like to thank founder Dr. Ashok K. Chauhan and Chancellor Mr. Atul Chauhan, Amity University Uttar Pradesh, Noida India, for providing necessary support and facilities.

  1. Author contribution: Ms. Ruchika Mittal and Gauri Srivastava are PhD scholars and working on biotransformation of alkaloids and monoterpenes. Both have surveyed and collected literature, and typewrite the manuscript. Deepak Ganjewala: Analyses of research reports, interpretation, execution and manuscript writing.

  2. Research funding: None declared.

  3. Conflict of interest statement: All authors have no conflict of interest.

  4. Consent for publication: All authors are agreed for submission of this paper.

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Received: 2021-07-04
Accepted: 2021-11-14
Published Online: 2021-12-07
Published in Print: 2022-05-25

© 2021 Walter de Gruyter GmbH, Berlin/Boston

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