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Licensed Unlicensed Requires Authentication Published by De Gruyter December 26, 2022

Tissue specific changes of phytochemicals, antioxidant, antidiabetic and anti-inflammatory activities of tea [Camellia sinensis (L.)] extracted with different solvents

  • Tania Baishya , Priya Das , Gouhar Jahan Ashraf , Tarun Kumar Dua ORCID logo , Paramita Paul , Gouranga Nandi , Malay Bhattacharya and Ranabir Sahu ORCID logo EMAIL logo

Abstract

Different parts of Camellia sinensis (L.) were extracted with solvents according to polarity, and the extracts’ phytochemical profiling and biological activities were examined. The total phenolic (TPC) and total flavonoid (TFC) contents increased with the increasing polarity of the solvent which met its maximum in polar solvents. The increasing antioxidant, anti-inflammatory and antidiabetic activities were recorded with increasing polarity of solvents which showed hydroalcoholic as best solvent. The strong and significant correlation was among the TPC, TFC, DPPH, anti-inflammatory and antidiabetic activities for different parts of tea. HPTLC study of individual phenolic acids, epigallocatechin gallate, gallocatechin and theaflavin met their maximum level of content with polar solvents like hydroalcohol, methanol and water mostly in mainly tea leaves. Our finding suggested that the polar solvents and young leaves of tea were beneficial for obtaining extracts. On the other hand, phenolics were found to be potent antioxidant, anti-inflammatory and antidiabetic agent.


Corresponding author: Ranabir Sahu, Department of Pharmaceutical Technology, University of North Bengal, Darjeeling 734013, West Bengal, India, E-mail:

Funding source: University of North Bengal, India

Award Identifier / Grant number: 1504/R-2020

Funding source: University Grants Commission

Award Identifier / Grant number: No. F. 30-515/2020(BSR);12/02/2020

Funding source: Science and Engineering Research Board

Award Identifier / Grant number: SRG/2019/001910

  1. Author contributions: RS designed the experiments, supervised the entire work. TB, PD and GJA performed the entire work. TKD, PP and GN participated in the entire work. RS, TB, PD, GJA, TKD, PP, GN and MB wrote the manuscript. All authors read and approved the final manuscript.

  2. Research funding: The financial support of SERB-SRG (file no. SRG/2019/001910), India, UGC-SRG [No. F. 30–515/2020(BSR); 12/02/2020], India, and the University assistance/support for the research project (Ref. No. 1504/R-2020), University of North Bengal, India, are greatly acknowledged.

  3. Conflict of interest statement: The authors declare that they have no conflict of interest.

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Received: 2022-08-17
Accepted: 2022-12-06
Published Online: 2022-12-26
Published in Print: 2023-05-25

© 2022 Walter de Gruyter GmbH, Berlin/Boston

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