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Summary
Magnetic drug targeting (MDT) is a new approach in local cancer therapy. Starch coated magnetite nanoparticles bound to the chemotherapeutic agent mitoxantrone can be enriched in the tumor region of a VX2 squamous cell carcinoma in rabbits. Using fluorescence-microscopy we showed enrichment of the chemotherapeutic agent in its site of action, the DNA.
Received: 2005-9-19
Accepted: 2005-10-28
Published Online: 2009-9-25
Published in Print: 2006-2-1
© by Oldenbourg Wissenschaftsverlag, München