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A zinc-based preparation of Siddha medicine, Naga Parpam (NP), is prescribed in the treatment of a variety of diseases. In folklore practice, NP is added as an ingredient in medicaments to treat obesity. Hence it was studied for antihyperlipidemic activity in cholesterol-fed rats with continuous administration for 30 days in doses of 10 and 20 mg / kg body weight. The drug prevented the elevation of total cholesterol, triglycerides, low-density lipoproteins (LDL) and very low-density lipoproteins (VLDL) in serum, liver and heart tissues in a dose-dependent manner when compared to control animals.
Keywords: Naga Parpam; antihyperlipidemic activity
Published Online: 2009-2-3
©2011 Walter de Gruyter GmbH & Co. KG, Berlin/Boston
