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BY-NC-ND 3.0 license Open Access Published by De Gruyter Open Access September 1, 2004

The synthesis and the structure elucidation of N,O-diacetyl derivative of cyclic 3-hydroxymelatonin

Aleksandra Siwicka, Russel Reiter, Dun Tian, Krystyna Wojtasiewicz, Andrezej Leniewski, Jan Maurin, Dariusz Błachut and Zbigniew Czarnocki
From the journal Open Chemistry


Melatonin was subjected to an oxidation to give 3-hydroxymelatonin. All spectroscopic data for this compound were collected. Ab initio calculations for both possible configurations were performed. X-ray data on N,O-diacetyl derivative of 3-hydroxymelatonin allowed the unambigous structure determination.

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Published Online: 2004-9-1
Published in Print: 2004-9-1

© 2004 Versita Warsaw

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