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BY-NC-ND 3.0 license Open Access Published by De Gruyter Open Access December 23, 2008

Structure, conformation and hydrogen bonding of two amino-cycloalkanespiro-5-hydantoins

Petar Todorov, Rosica Petrova, Emilia Naydenova and Boris Shivachev
From the journal Open Chemistry


The crystal structures of 3-amino-cycloheptanespiro-4′-imidazolidine-2′,5′-dione (I) {systematic name: 3-amino-1,3-diazaspiro[4.6] undecane-2,4-dione} and 3-amino-cyclooctanespiro-4′-imidazolidine-2′,5′-dione (II) {systematic name: 3-amino-1,3-diazaspiro[4.7] dodecane-2,4-dione}, have been determined. In both compounds the polar hydantoin groups cause molecules to aggregate via N-H...O and N-H...N interactions, forming a layer structure, in which the cycloalkane rings project outwards from the central, more polar, region. The observed molecular structure is compared with that calculated by density functional theory methods.

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Published Online: 2008-12-23
Published in Print: 2009-3-1

© 2009 Versita Warsaw

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 3.0 License.

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