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BY-NC-ND 3.0 license Open Access Published by De Gruyter Open Access June 17, 2010

Interaction of methoxy- and methylenedioxyamphetamines with carbon and polymeric adsorbents in polar liquids

  • Waldemar Tomaszewski EMAIL logo , Vladimir Gun’ko , Roman Leboda and Jadwiga Skubiszewska-Zięba
From the journal Open Chemistry


Solid phase extraction (SPE) of methoxy- and methylenedioxyamphetamines from diluted aqueous solutions was investigated on carbon and polymeric adsorbents of different textures and chemical compositions. Those adsorbents were applied cartridges packed with three chemically modified carbons prepared from plum stones (initial A2PS, oxidized A2PS-O, and reduced A2PS-H) and commercially available adsorbents (polymeric LiChrolut EN, graphitized Hypercarb and Carboprep). Several factors influence the recovery rates of amphetamine derivatives such as the polarity of adsorbates (free energy of salvation), the specific surface area and surface composition of adsorbents, and the solvent characteristics. Different combinations of these factors affect the recovery rate (R1) for high- and low-surface area adsorbents. The minimal R1 values are observed for an amphetamine derivative at a maximal solvation effect and for a set of amphetamines adsorbed on graphitized carbons.

[1] Annual Report 2006, European Monitoring Centre for Drugs and Drug Addiction, Search in Google Scholar

[2] D. de Boer, I. Bosman, Pharm. World Sci. 26, 110 (2004) in Google Scholar

[3] L.H. Ling, C. Marchant, N.A. Buckley, M. Prior, R.J. Irvine, Med. J. Aust. 174, 453 (2001) 10.5694/j.1326-5377.2001.tb143372.xSearch in Google Scholar

[4] S.P. Elliott, J. Anal. Toxicol. 24, 85 (2000) 10.1023/A:1017205419893Search in Google Scholar

[5] J.P. Franke, R.A. de Zeeuw, J. Chromatogr. B 713, 51 (1998) in Google Scholar

[6] B.S. De Martinis, A.J. Barnes, K.B. Scheidweiler, M. A. Huestis, J. Chromatogr. B 852, 450 (2007) in Google Scholar PubMed PubMed Central

[7] A. Namera et al., J.Chromatogr. A 1208, 71 (2008) in Google Scholar PubMed

[8] A. Nakamoto et al., Forensic Toxicol. 24, 75 (2006) in Google Scholar

[9] T. Kumazawa et al., J. Pharm. Biomed. Anal. 44, 602 (2007) in Google Scholar PubMed

[10] C. Hasegawa et al., Anal. Bioanal. Chem. 389, 563 (2007) in Google Scholar PubMed

[11] K. Kudo, T. Ishida, K. Hara, S. Kashimura, A. Tsuji, N. Ikeda, J. Chromatogr. B 855, 115 (2007) in Google Scholar PubMed

[12] G. Boatto et al., J. Chromatogr. B 814, 93 (2005) in Google Scholar

[13] W. Tomaszewski, V.M. Gun’ko, R. Leboda, J. Skubiszewska-Zięba, J. Colloid Interface Sci. 282, 261 (2005) in Google Scholar

[14] R. Leboda, A. Łodyga, Chem. Anal. (Warsaw) 36, 103 (1991) Search in Google Scholar

[15] D. Błachut, K. Wojtasiewicz, Z. Czarnocki, Forensic Sci. Int. 127, 45 (2002) in Google Scholar

[16] F.T. Noggle, C. R. Clark, J. DeRuiter, J. Chromatogr. Sci. 27, 607 (1989) 10.1093/chromsci/27.10.607Search in Google Scholar

[17] R.F. Borch, M.D. Bernstein, H.D. Durst, J. Am. Chem. Soc. 93, 2897 (1971) in Google Scholar

[18] A.W. Adamson, A.P. Gast, Physical Chemistry of Surfaces, 6th edition (Wiley, New York, 1997) Search in Google Scholar

[19] D.D. Do, C. Nguyen, H.D. Do, Colloids Surf. A 187–188, 51 (2001) in Google Scholar

[20] B. Platzer, G. Maurer, Fluid Phase Equilibr. 51, 223 (1989) in Google Scholar

[21] S.W. Provencher, Comp. Phys. Comm. 27, 213 (1982) in Google Scholar

[22] (a) M.W. Schmidt et al., J. Comput. Chem. 14, 1347 (1993) 10.1002/jcc.540141112Search in Google Scholar

[23] A.V. Nemukhin, B.L. Grigorenko, A.A. Granovsky, Moscow University Chemistry Bulletin 45(2), 75 (2004) Search in Google Scholar

[24] M.J. Frisch et al., Gaussian 03, Revision E.01 (Gaussian, Inc., Wallingford CT, 2004) Search in Google Scholar

[25] R. Leboda, V.M. Gun’ko, W. Tomaszewski, B.J. Trznadel, J. Colloid Interface Sci. 238, 489 (2001) in Google Scholar PubMed

[26] R. Leboda, V.V. Turov, W. Tomaszewski, V.M. Gun’ko, J. Skubiszewska-Zięba, Carbon 40, 389 (2002) in Google Scholar

[27] W. Tomaszewski, V.M. Gun’ko, R. Leboda, J. Skubiszewska-Zięba, J. Colloid Interface Sci. 266, 388 (2003) in Google Scholar

[28] V.M. Gun’ko et al., J. Colloid Interface Sci. 323, 6 (2008) in Google Scholar PubMed

Published Online: 2010-6-17
Published in Print: 2010-8-1

© 2010 Versita Warsaw

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 3.0 License.

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