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BY-NC-ND 3.0 license Open Access Published by De Gruyter Open Access May 29, 2012

Preparation of a series of N-alkyl-3-boronopyridinium halides and study of their stability in the presence of hydrogen peroxide

Yevgen Karpichev, Hubert Matondo, Illia Kapitanov, Oleksandr Savsunenko, Marc Vedrenne, Verena Poinsot, Isabelle Rico-Lattes and Armand Lattes
From the journal Open Chemistry


A simple and efficient protocol for the preparation of a series of N-alkyl-3-boronopyridinium salts is described which requires exposure of 3-pyridineboronic acid neopentylglycol ester and corresponding alkyle halide to microwave irradiation followed by boronic ester hydrolysis. The technique employed drastically reduces the reaction time and prevents thermal degradation and the formation of side products. Water solutions of the obtained boronopyridinium salts are shown to be stable at room temperature in wide pH range as well as in the presence of hydrogen peroxide at pH 10.0 for 72 h.

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Published Online: 2012-5-29
Published in Print: 2012-8-1

© 2012 Versita Warsaw

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 3.0 License.

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