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BY-NC-ND 3.0 license Open Access Published by De Gruyter Open Access July 19, 2013

Aqueous photocatalytic oxidation of prednisolone

  • Deniss Klauson EMAIL logo , Jana Pilnik-Sudareva , Natalja Pronina , Olga Budarnaja , Marina Krichevskaya , Aleksandr Käkinen , Katre Juganson and Sergei Preis
From the journal Open Chemistry


The research into the aqueous photocatalytic oxidation of the anti-inflammatory drug prednisolone was undertaken with P25 titanium dioxide (Evonik) and visible light-sensitive sol-gel synthesized titania-based photocatalysts containing carbon, sulphur, and iron. Possible prednisolone photocatalytic oxidation reaction pathways were proposed based on a number of oxidation by-products determined in the present study. The prednisolone adsorption properties, effects of initial prednisolone concentration, pH, usual wastewater matrix admixtures, like carbamide and sucrose, were studied. The nontoxicity of doped catalysts towards Tetrahymena thermophila, a ciliate protozoa present in the activated sludge, indicated their lower oxidative ability compared to P25, but also implied their potential application in pre-treatment of toxic hazardous materials under VIS or solar radiation before the biological degradation stage.

[1] A. Y.C. Lin, T.H. Yu, S.K. Lateef, J. Hazard. Mater. 167, 1163 (2009) in Google Scholar

[2] M. DellaGreca, A. Fiorentino, M. Isidori, M. Lavorgna, L. Previtera, M. Rubino, F. Temussi, Chemosphere 54, 629 (2004) in Google Scholar

[3] Y. Kitaichi, A. Miyamoto, K. Uchikura, J. Health Sci. 56, 547 (2010) in Google Scholar

[4] H. Chang, J.Y. Hu, B. Shao, Environ. Sci. Technol. 41, 3462 (2007) in Google Scholar

[5] K. Ikehata, N.J. Naghashkar, M.G. Ei-Din, Ozone Sci. Eng. 28, 353 (2006) in Google Scholar

[6] B. Langlais, D. Reckow, D. Brink, Ozone in Water Treatment. Application and engineering (Lewis Publishers, Inc., Chelsea, 1991) Search in Google Scholar

[7] B. K. Nandi, R. Uppaluri, M.K. Purkait, Appl. Clay Sci. 42, 102 (2008) in Google Scholar

[8] S. Liu, G.-G. Ying, J.-L. Zhao, F. Chen, B. Yang, L.-J. Zhou, H.-j. Lai, J. Chromatography A 1218, 1367 (2011) in Google Scholar

[9] D. Klauson, J. Babkina, K. Stepanova, M. Krichevskaya, S. Preis, Catal. Today 151, 39 (2010) in Google Scholar

[10] R. J.S. Lewis, Hawley’s Condensed Chemical Dictionary, 14 edition (John Wiley and Sons, Inc., Chelsea, 2001) Search in Google Scholar

[11] D. Hansch, A. Leo, D. Hoekman, Exploring QSAR — Hydrophobic, Electronic, and Steric Constants (American Chemical Society, Washington, DC, 1995) Search in Google Scholar

[12] S. H. Yalkowski, Y. He, Handbook of Aqueous Solubility data: An Extensive Compilation of Aqueous Solubility data for Organic Compounds Extracted from the AQUASOL dATAbase (CRC Press LLC, Boca Raton, FL, 2003) in Google Scholar

[13] M. J. O’Neil, The Merck Index — An Encyclopedia of Chemicals, Drugs and Biologicals., 13 edition (Merck and Co., Inc, Whitehouse Station, NJ, 2001) Search in Google Scholar

[14] US EPA, Estimation Program Interface (EPI) Suite. US EPA, Estimation Program Interface (EPI) Suite. Ver. 3.12 (US Environmental Protection Agency (EPA), USA, November 30, 2004) Search in Google Scholar

[15] B. Sun, M. Sato, J.S. Clements, J. Electrostatics 39, 189 (1997) in Google Scholar

[16] D. Bahnemann, Solar Energy 77, 445 (2004) in Google Scholar

[17] R. W. Matthews, Water Research 20, 569 (1986) in Google Scholar

[18] J. Chen, D.F. Ollis, W.H. Rulkens, H. Bruning, Water Research 33, 669 (1999) in Google Scholar

[19] V. Brezová, Š. Vodný, M. Veselý, M. Čeppan, L. Lapčík, J. Photochem. Photobiol. A 56, 125 (1991) in Google Scholar

[20] Y. Zhang, J.C. Crittenden, D.W. Hand, D.L. Perram, Environ. Sci. Technol. 28, 435 (1994) in Google Scholar

[21] C. Lettmann, K. Hildenbrand, H. Kisch, W. Macyk, W.F. Maier, Appl. Catal. B 32, 215 (2001) in Google Scholar

[22] T. Ihara, M. Miyoshi, Y. Iriyama, O. Matsumoto, S. Sugihara, Appl. Catal. B 42, 403 (2003) in Google Scholar

[23] Z. Wang, W. Cai, X. Hong, X. Zhao, F. Xu, C. Cai, Appl. Catal. B 57, 223 (2005) in Google Scholar

[24] D. Klauson, E. Portjanskaja, S. Preis, Environ. Chem. Lett. 6, 35 (2008) in Google Scholar

[25] D. Klauson, E. Portjanskaya, O. Budarnaja, M. Krichevskaya, S. Preis, Catal. Comm. 11, 715 (2010) in Google Scholar

[26] Z. Liu, D.D. Sun, P. Guo, J.O. Leckie, Chem. Eur. J. 13, 1851 (2007) in Google Scholar

[27] S. J. Kirkpatrick, Dental Mater. 21, 21 (2005) in Google Scholar

[28] G. Boeije, R. Corstanje, A. Rottiers, D. Schowanek, Chemosphere 38, 699 (1999) in Google Scholar

[29] T. Karpova, S. Preis, J. Kallas, Int. J. Photoenergy 2007, Article ID 53853 (2007) 10.1155/2007/53853Search in Google Scholar

[30] L. S. Clesceri, A.E. Greenberg, R.R. Trussel, Standard methods for the examination of water and wastewater (APHA, AWWA, WPCF, Washington, DC, 1989) Search in Google Scholar

[31] M. Mortimer, K. Kasemets, A. Kahru, Toxicology 269, 182 (2010) in Google Scholar PubMed

[32] E. Vindimian, MSExcel macro REGTOX EV7.0.5.xls (Eric Vindimian, France) 2011 Search in Google Scholar

[33] S. Preis, M. Krichevskaya, Y. Terentyeva, A. Moiseev, J. Kallas, J. Adv. Oxid. Technol. 5, 77 (2002) 10.1515/jaots-2002-0110Search in Google Scholar

[34] M. Krichevskaya, T. Malygina, S. Preis, J. Kallas, Water Sci. Technol. 44, 1 (2001) Search in Google Scholar

[35] M. Krichevskaya, A. Kachina, T. Malygina, S. Preis, J. Kallas, Int. J. Photoenergy 5, 81 (2003) in Google Scholar

[36] D. Klauson, S. Preis, Int. J. Photoenergy 2007, Article ID 89359 (2007) 10.1155/2007/89359Search in Google Scholar

[37] K. Mogyorósi, N. Balázs, D.F. Srankó, E. Tombácz, I. Dékány, A. Oszkó, P. Sipos, A. Dombi, Appl. Catal. B 96, 577 (2010) in Google Scholar

[38] D. M. Metzler, M.H. Li, A. Erdem, C.P. Huang, Chem. Eng. J. 170, 538 (2011) in Google Scholar

[39] L. Brunet, D.Y. Lyon, E.M. Hotze, P.J.J. Alvarez, M.R. Wiesner, Environ. Sci. Technol. 43, 4355 (2009) in Google Scholar

[40] P. Madoni, Water Research 28, 67 (1994) in Google Scholar

[41] M. P. Sauvant, D. Pepin, E. Piccinni, Chemosphere 38, 1631 (1999) in Google Scholar

[42] G. Esteban, C. Tellez, L.M. Bautista, Water Research 25, 967 (1991) in Google Scholar

Published Online: 2013-7-19
Published in Print: 2013-10-1

© 2013 Versita Warsaw

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 3.0 License.

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