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BY-NC-ND 3.0 license Open Access Published by De Gruyter Open Access July 19, 2013

In vitro biological activity comparison of some hydroxyapatite-based composite materials using simulated body fluid

  • Melinda Czikó EMAIL logo , Erzsébet-Sára Bogya , Réka Barabás , Liliana Bizo and Răzvan Stefan
From the journal Open Chemistry

Abstract

Hydroxyapatite composites are the main biomaterials used for metal implant coatings. Their in vitro study is very important. That is why their behavior was monitored in simulated body fluid (SBF), which is a solution with ion concentrations and pH value similar to those of human blood plasma. Silica, chitosan and gelatin-doped hydroxyapatite-based biomaterials were studied in SBF; the samples were characterized pre-, during and post-SBF immersion using infra-red, scanning and transmission electron spectroscopy and X-ray diffraction methods. The solubility of materials in SBF was determined, and the variation of Ca2+ and phosphorus concentration was also recorded during SBF experiments. The results were compared and their in vitro biological activity was determined.

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Published Online: 2013-7-19
Published in Print: 2013-10-1

© 2013 Versita Warsaw

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 3.0 License.

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