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BY-NC-ND 3.0 license Open Access Published by De Gruyter Open Access December 1, 2006

Indoor exposure to chemical and biological agents and health efects in primary school children

Ljiljana Stosic, Suzana Milutinovic, Maja Nikolic, Dragana Nikic, Olivera Radulovic and Aleksandra Stankovic
From the journal Open Medicine


The aim of this study has been to estimate effects of indoor air pollutants on children’s health. An anamnestic retrospective study was done on 1074 children aged between 7 and 11 years old who lived in Nis (Serbia). An original questionnaire was used in an interview between training physicians and children’s parents. Interview data were processed by using Microsoft Excel and Epiinfo 6. The investigation determined that children who were more often exposed to combustion by-products had respiratory and nonspecific symptoms. Parental smoking was strongly associated with wheezing, bronchitis, headache and fatigue. There was no association between health and keeping pets, apart from partial nasal congestion. Presence of insects (e.g., cockroaches) and rats in households was a significant risk factor for all symptoms and diseases estimated except for asthma and pneumonia. Homes abundant in textiles were the cause of nasal congestion, wheezing and fatigue in children. Old mattresses were associated with respiratory symptoms, bronchitis, and nonspecific symptoms. It has been concluded that indoor air quality plays a major role in children’s health. Sources of indoor air pollution are present in every home. Being aware of the risks associated with indoor air quality problems, consequently, leads to their mitigation.

[1] R.A. Fenske, K.G. Black, K.P. Elkner, C. Lee and M.M. Mether: “Potential exposure and health risks of infants following indoor residential pesticide applications”, Am. J. Public. Health, (1990), Vol. 80, pp. 13–15. Search in Google Scholar

[2] K.R. Smith, J.M. Samet, I. Romieu and N. Bruce: “Indoor air pollution in developing countries and acute lower respiratory infections in children”, Thorax, Vol. 55, (2000), pp. 518–522. in Google Scholar

[3] A.P. Jones: “Asthma and domestic air quality”, Soc. Science Med., Vol. 47, (1998), pp. 755–764. in Google Scholar

[4] G. Viegi, M. Simoni, A. Scognamiglio, S. Baldacci, F. Pistelli, L. Carrozzi and I. Annesi-Maesano.: “Indoor air pollution and airway disease”, Int. J. Tuberc. Lung. Dis., Vol. 8, (2004), pp. 401–415. Search in Google Scholar

[5] B. Levesque, S. Allaire, D. Gauvin, P. Koutrakis, S. Gingras, M. Rhainds, H. Prud’Homme and J.F. Duchesne: “Wood-burning appliances and indoor air quality”, Sci. Total Environ., Vol. 17, (2001), pp. 47–62. in Google Scholar

[6] Y. Tesfaigzi, S.P. Singh, J.E. Foster, J. Kubatko, E.B. Barr, P.M. Fine, J.D. Mc-Donald, F.F. Hahn and J.L. Mauderly: “Health effects of subchronic exposure to low levels of wood smoke in rats”, Toxicol. Sci., Vol. 65, (2002), pp. 115–125. in Google Scholar PubMed

[7] M.A. Schei, M.A. Schei, J.O. Hessen, K.R. Smith, N. Bruce, J. McCracken and V. Lopez: “Childhood asthma and indoor wood smoke from cooking in Guatemala”, J. Expo. Anal. Environ. Epidemiol., Vol. 14, (2004), pp. 110–117. in Google Scholar PubMed

[8] A.J. Venn, M. Cooper, M. Antoniak, C. Laughlin, J. Britton and S.A. Lewis: “Effects of volatile organic compaunds, damp, and other environmental exposures in the home on wheezing illnes in children”, Thorax, Vol. 58, (2003), pp. 955–960. in Google Scholar PubMed PubMed Central

[9] M.L. Bur, H.R. Anderson, J.B. Austin, L.S. Harkins, B. Kaur, D.P. Strachan and J.O. Warner: “Respiratory symptoms and home environment in children; a national survey”, Thorax, Vol. 54, (1999), pp. 27–32. Search in Google Scholar

[10] J.D. Shenkin, B. Broffitt, S.M. Levy and J.J. Warren: “The assotiation between environmental tobacco smoke and primary tooth caries”, J. Public. Health. Dent., Vol. 64, (2004), pp. 184–186. Search in Google Scholar

[11] K. Yolton, K. Dietrich, P. Auinger, B.P. Lanphear and R. Hornung: “Exposure to Environmental Tobacco Smoke and Cognitive Abilities among U.S. Children and Adolescents”, Environ. Health Perspect, Vol. 113, (2005), pp. 98–103. in Google Scholar PubMed PubMed Central

[12] M. Sexton, N.L. Fox and J.R. Hebel: “Prenatal exposure to tobacco: II. Effects on cognitive functioning at age three”, Int. J. Epidemiol., Vol. 19, (1990), pp. 72–77. Search in Google Scholar

[13] R.S. Strauss: “Environmenral tobacco smoke and serum vitamin C levels in children”, Pediatrics, Vol. 107, (2001), pp. 540–542. in Google Scholar PubMed

[14] P. Tutka, M. Wielos and W. Zatonski: “Exposure to environmental tobacco smoke and children health”, Int. J. Occup. Med. Environ. Health., Vol. 15, (2002), pp. 325–335. Search in Google Scholar

[15] B.P. Leadere, K. Belanger, E. Triche, T. Holford, D.R. Gold, Y. Kim, T. Jankun, P. Ren, J. McSharry, T.A.E. Platts-Mills, M.D. Chapman and M.B. Bracken: “Dust mite, cockroach, cat, and dog allergen concentrations in homes of asthmatic children in the northeastern United States: imact of socioeconomic factors and population density”, Environ. Health Perspect, Vol. 110, (2002), pp. 419–425. in Google Scholar PubMed PubMed Central

[16] A. Ernst and J.D. Zibrak: “Carbon monoxide poising”, N. Engl. J. Med., Vol. 72, (1998), pp. 1603–1608. in Google Scholar PubMed

[17] B.D. Ostro, M.J. Lipsett, J.K. Mann and M.B. Wiener: “Indoor air pollution and asthma. Results from a panel study”, Am. J. Respir. Crit. Care. Med., Vol. 149, (1994), pp. 1389–1390. Search in Google Scholar

[18] G. Touloumi, K. Katsouyanni, D. Zmirou, J. Schwartz, C. Spix, A.P. de Leon, A. Tobias, P. Quennel, D. Rabczenko, L. Bacharova, L. Bisanti, J.M. Vonk and A. Ponka: “Short-term effects of ambient oxidants exposure on mortality: a combined analysis within the APHEA project”, Am. J. Epidemiol., Vol. 7, (1997), pp. 225–230. in Google Scholar

[19] S.A. McKenzie and A. Bush: “Difficult asthma in children”, rArch. Dis. Child, Vol. 88, (2003), pp. 168–169. in Google Scholar

[20] B.L. Hajnal, C. Braun-Fahrlander, L. Grize, M. Gassner, H.S. Varonier, J.C. Vuille, B. Wuthrich and F.H. Sennhauser: “Effects of environmental tobacco smoke exposure on respiratory symptoms in children. SCARPOL Team. Swiss Study on Childhood Allergy and respiratory Symptoms with Respect to Air Pollution, Climate and Pollen”, Schweiz Med Wochenschr, Vol. 15, (1999), pp. 723–730. Search in Google Scholar

[21] H.A. Burge: “Risk Associated With Indoor air Infectious Aerosols”, Toxicol. Ind. Health, Vol. 6, (1990), pp. 263–273. Search in Google Scholar

[22] C. Svanes, J. Heinrich, D. Jarvis, S. Chinn, E. Omenaas, A. Gulsvik, N. Kunzli and P. Burney: “Pet-keeping in childhood and adult asthma and hay fever: European community respiratory health survey”, J. Allergy Clin. Immunol., Vol. 112, (2003), pp. 289–300. in Google Scholar

[23] P. Carrer, M. Maroni, D. Alcini and D. Cavallo: “Allergens in indoor air: environmental assessment and health effects”, Sci. Total Environ., Vol. 270, (2001), pp. 33–42. in Google Scholar

[24] P. Carrer and G. Moscato: “Biological pollution and allergic diseases”, G. Ital. Med. Lav. Ergon., Vol. 26, (2004), pp. 370–374. Search in Google Scholar

[25] A.A. Litonjua, V.J. Carey, H.A. Burge, S.T. Weiss and D.R. Gold: “Exposure to cockroach allergen in the home is associated with incident doctor-diagnosed asthma and recurrent wheezing”, J. Allergy Clin. Immunol., Vol. 107, (2001), pp. 41–47. in Google Scholar PubMed

[26] A. Woodcock and A. Custovic: “Avoiding exposure to indoor allergens”, BMJ, Vol. 316, (1998), pp. 1075–1080. Search in Google Scholar

[27] J. J. Jaakkkola, L. Oie, P. Nafstad, G. Botten, S. O. Samuelsen and P. Magnus: “Interior surface materials in the home and the development of bronchial obstruction in young children in Oslo, Norway”, Am. J. Public Health, Vol. 89, (1999), pp. 188–199. in Google Scholar

Published Online: 2006-12-1
Published in Print: 2006-12-1

© 2006 Versita Warsaw

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