We report a 71-year-old male with microscopic polyangiitis (MPA) who developed sudden-onset, progressive, bilateral visual loss associated with a relapse of MPA symptoms. The patient was referred to our hospital, and treated with intravenous pulse steroid therapy and high-dose oral prednisolone. Although the right eye remained vision deficient, visual acuity in the left eye recovered. Ocular manifestations of MPA are quite uncommon. This case emphasizes the necessity of early detection and initiation of prompt therapy where ocular manifestations of MPA occur.
 Rarok AA, Limburg PC, Kallenberg CG. Neutrophilactivating potential of antineutrophil cytoplasm autoantibodies. J Leukoc Biol, 2003, 7, 3–15 http://dx.doi.org/10.1189/jlb.120261110.1189/jlb.1202611Search in Google Scholar PubMed
 Guillevin L, Durand-Gasselin B, Cevallos R, et al. Microscopic polyangiitis: clinical and laboratory findings in eighty-five patients. Arthritis Rheum, 1999, 42, 421–430 http://dx.doi.org/10.1002/1529-0131(199904)42:3<421::AID-ANR5>3.0.CO;2-610.1002/1529-0131(199904)42:3<421::AID-ANR5>3.0.CO;2-6Search in Google Scholar
 Yoshida M. Clinical analysis of anti-neutrophil cytoplasmic antibody in diagnosis of collagen diseases. Nippon Naika Gakkai Zasshi(Japanese). 2003, 92, 1941–1947 http://dx.doi.org/10.2169/naika.92.194110.2169/naika.92.1941Search in Google Scholar
 Tamura N, Matsudaira R, Hirashima M, et al. Two cases of refractory Wegener’s granulomatosis successfully treated with rituximab. Intern Med, 2007, 46:409–414 http://dx.doi.org/10.2169/internalmedicine.46.615610.2169/internalmedicine.46.6156Search in Google Scholar
 Duran E, Merkel PA, Sweet S, Swan N, Babikian VL. ANCA-associated small vessel vasculitis presenting with ischemic optic neuropathy. Neurology, 2004, 62, 152–153 10.1212/WNL.62.1.152Search in Google Scholar
 Altaie R, Ditizio F, Fahy GT. Microscopic polyangitis presenting with sub-acute reversible optic neuropathy. Eye, 2004, 19, 363–365 http://dx.doi.org/10.1038/sj.eye.670147910.1038/sj.eye.6701479Search in Google Scholar
© 2011 Versita Warsaw
This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 3.0 License.