Abstract
Systemic lupus erythematosus (SLE) and myasthenia gravis (MG) are autoimmune diseases, their association in the same patient being rarely described. Here, we report a case of SLE in a 19-year-old girl who within 2 years of the diagnosis of SLE developed MG, and underwent thymectomy for a benign thymoma immediately thereafter.
[1] Schofield RH. Autoimmune thyroid disease in systemic lupus erythematosus and Sjogren’s syndrome. Clin Exp Rheumatol 1996; 14:321–330 Search in Google Scholar
[2] Moutsopoulos HM, Klippel JH, Pavlidis, Wolf RO, Sweet JB, Steinberg AD et al. Correlative histologic and serologic findings of sicca syndrome in patients with systemic lupus erythematosus. Arthritis Rheum 1980; 23:36–40 http://dx.doi.org/10.1002/art.178023010710.1002/art.1780230107Search in Google Scholar PubMed
[3] Karpatkin S. Autoimmune thrombocytopaenicpurpura. Semin Haematol 1985;22:260–288 Search in Google Scholar
[4] McDonagh JE, Isenberg D.A. Development of additional autoimmune diseases in a population of patients with systemic lupus erythematosus. Annals of rheumatic diseases 2000; 59(3):230–232 http://dx.doi.org/10.1136/ard.59.3.23010.1136/ard.59.3.230Search in Google Scholar PubMed PubMed Central
[5] Castrejón I, Shum K, Tseng CE, Askanase A. Association between myasthaenia gravis and systemic lupus erythematosus: three case reports and review of the literature. Scandinavian Journal of Rheumatology 2011;40(6):486–490 http://dx.doi.org/10.3109/03009742.2011.57507710.3109/03009742.2011.575077Search in Google Scholar PubMed
[6] Studart SA, Rodrigues CL, Soares CB et al. Systemic Lupus Erythematosus with muscle weakness due to Myasthenia Gravis. Revista Brasileira de Reumatologia 2011; 51(3):289–294 http://dx.doi.org/10.1590/S0482-5004201100030001010.1590/S0482-50042011000300010Search in Google Scholar
[7] Hrycek A. A sequence of pathologic events in a patient after thymectomy for myasthenia gravis. Rheumatology International 2012;32(1):245–248 http://dx.doi.org/10.1007/s00296-009-1301-010.1007/s00296-009-1301-0Search in Google Scholar PubMed
[8] Louzir B, Ben Abdelhafidh N, Bahri M, M’Sadek F, Ksontini I, Boussema E, Othmani S. Association of systemic lupus erythematosis and myasthenia gravis. A new case report. La Tunisie Medicale 2003; 81(12):963–966 Search in Google Scholar
[9] Vaiopoulos G, Sfikakis PP, Kapsimali V, Bokil K, Panayiotidis P, Aessopos A, Tsokos GC, Kaklamanis P. The association of systemic lupus erythematosis and myasthenia gravis. Postgraduate Medicine Journal 1994; 70: 741–745 http://dx.doi.org/10.1136/pgmj.70.828.74110.1136/pgmj.70.828.741Search in Google Scholar PubMed PubMed Central
[10] Park MJ, Kim YA, Lee SS, Kim BC, Kim MK, Cho KH. Appearance of systemic lupus erythematosus in patients with myasthenia gravis following thymectomy: two case reports. Journal of Korean Medical Science 2004; 19(1): 134–136 http://dx.doi.org/10.3346/jkms.2004.19.1.13410.3346/jkms.2004.19.1.134Search in Google Scholar PubMed PubMed Central
[11] Omar HA, Alzahrani MA, Al Bshabshe AA et al. Systemic lupus erythematosus after thymectomy for myasthenia gravis: a case report and review of the literature. Clinical and Experimental Nephrology 2010; 14(3):272–276 http://dx.doi.org/10.1007/s10157-009-0256-510.1007/s10157-009-0256-5Search in Google Scholar PubMed
[12] Casado E, Gratacós J, Tolosa C, Martinez JM, Ojanguren I, Ariza A et al. Antimalarial myopathy: an underdiagnosed complication?Prospective longitudinal study of 119 patients. Annals of Rheumatic Diseases 2006; 65(3):385–390 http://dx.doi.org/10.1136/ard.2004.02320010.1136/ard.2004.023200Search in Google Scholar PubMed PubMed Central
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