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BY-NC-ND 3.0 license Open Access Published by De Gruyter Open Access July 8, 2014

The role of genetic and other biomarkers in NSCLC prognosis

Diana Schveigert, Saulius Cicenas, Jaroslav Bublevic, Renatas Askinis, Virginijus Sapoka and Janina Didziapetriene
From the journal Open Medicine

Abstract

The development of non-small-cell lung cancer (NSCLC) is a multistep process, which is triggered and maintained by various factors. Many steps of non-small-cell lung carcinogenesis, risk factors and biomarkers have been identified; however no consistent model has been established of personalized medicine for these patients. Distinct various gene expression, products of mutated genes and other markers such as circulating nucleic acids or tumor cells has been proven to be potential biomarkers of non-small cell lung cancer as well as potential targets for new treatment strategies. This article will highlight promising biomarkers in non-small cell lung cancer prognosis.

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Published Online: 2014-7-8
Published in Print: 2014-6-1

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