Abstract
Studies of the interaction between the zinc-peptide complex ([Zn(II)-Gly-Gly]+) and ninhydrin in aqueous and CTAB surfactant media were executed by the means of UV-visible spectrophotometry. The reaction rates (kobs and kψ) were determined in both media by varying different parameters such as pH, temperature and the concentration of the reactants and CTAB. The micellar binding constants and activation parameters were also calculated. The catalytic activity in the CTAB medium was found to be better than in the aqueous medium on the title reaction. The catalysis by CTAB is treated quantitatively by applying the model of the kinetic pseudo-phase of the micelle. Variation of the rate constant with the change of the CTAB concentration was used for the calculation of several kinetic parameters such as the binding constants (KB and KNin) and the micellar rate constant km. On basis of the experimental results, a probable mechanism is proposed.
Kurzfassung
Untersuchungen zur Wechselwirkung zwischen dem Zink-Peptid-Komplex ([Zn(II)-Gly-Gly]+) und Ninhydrin in wässrigen und CTAB-Tensidmedien wurden mittels UV-Vis-Spektrophotometrie durchgeführt. Die Reaktionsgeschwindigkeiten (kobs und kψ) wurden in beiden Medien durch Variieren verschiedener Parameter, wie pH, Temperatur und der Konzentration der Reaktanten und CTAB, bestimmt. Die Mizellenbindungskonstanten und Aktivierungsparameter wurden ebenfalls berechnet. Die katalytische Aktivität im CTAB-Medium erwies sich bei der Titelreaktion als besser als im wässrigen Medium. Die Katalyse durch CTAB wird quantitativ unter Anwendung des Modells der kinetischen Pseudophase der Mizelle behandelt. Die Variation der Geschwindigkeitskonstante mit der Änderung der CTAB-Konzentration wurde zur Berechnung mehrerer kinetischer Parameter verwendet, wie der Bindungskonstanten KB und KNin und der Mizellengeschwindigkeitskonstante km. Auf der Grundlage der experimentellen Ergebnisse wird ein wahrscheinlicher Mechanismus vorgeschlagen.
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