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Publicly Available Published by De Gruyter June 2, 2014

4-tert-Butoxy-1-ethoxy-1,3-bis(trimethylsilyloxy)-1,3-butadiene. A New Diene and its Application to the Synthesis of γ-Alkylidenetetronic Acids

  • Van Thi Hong Nguyen , Bui Duy Cam , Zafar Ahmed and Peter Langer EMAIL logo

A new approach to γ-alkylidenetetronic acids is reported which is based on Me3SiOTf-catalyzed [3+2] cyclization of 4-tert-butoxy-1,3-bis(trimethylsilyloxy)-1,3-butadiene with oxalyl chloride, orthogonal protection of the α-hydroxy group by benzylation and subsequent deprotection of the β-hydroxy group.

Graphical Abstract

 4-tert-Butoxy-1-ethoxy-1,3-bis(trimethylsilyloxy)-1,3-butadiene. A New Diene and its Application to the Synthesis of γ-Alkylidenetetronic Acids

4-tert-Butoxy-1-ethoxy-1,3-bis(trimethylsilyloxy)-1,3-butadiene. A New Diene and its Application to the Synthesis of γ-Alkylidenetetronic Acids

Received: 2013-2-20
Published Online: 2014-6-2
Published in Print: 2013-7-1

© 1946 – 2014: Verlag der Zeitschrift für Naturforschung

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