Abstract
In our search for the antiinflammatory activ principles of fat of badger and alp-marmot, used in folk-medicine as remedies against rheumatism and arthritis, eight known corticosteroids have been detected and identified in the lipophilic fraction of body fats of both animals. Enrichment and detection succeeded by using TLC, straight phase HPLC with diode array equipment, HR-GC on OV-1 capillary columns and GC/MS of the methyloxime-trimethylsilylated steroids. The amount of the detected steroids ranges from 30-40 mg/kg. The whole antiinflammatory activity of the fat, as measured in the rat paw edema test, results from these and further hitherto unidentified cortico-steroids.
© 1946 – 2014: Verlag der Zeitschrift für Naturforschung
This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 3.0 License.