The interpretation of civilization has always been controversial, and it is even difficult for academic circles to distinguish between civilization and culture. Researchers often use the method of scientific induction to generalize and define civilization from their respective angles. In fact, the concept of civilization is very complicated and difficult to explain from a single perspective. This article attempts to explore the multiple interpretations of civilization from the forward and reverse interaction of civilization development, different perspectives of civilization interpretation such as history, literature, and language, and the problem consciousness of civilization interpretation. From the perspective of history, civilization is formed by a series of specific historic events and social changes. From that of literature, civilization transcends specific historical events, is formed in the process of replacing old and new societies, and is of universal significance. Interpreted from the perspective of language signs, civilization is only an expression of human language signs, which are carriers of civilization, etc. As human society continues to develop, the interpretation of civilization continues to change. The meaning of civilization cannot be determined. We can only approach it through constant questioning and exploration. Because the understanding of civilization is multi-perspective, the interpretation of civilization is dynamic.