This work deals with the simulation-based investigation and control of optical systems that are mechanically influenced. Here, the focus is on the dynamic-optical modeling of vibration-sensitive, segmented mirror systems, which are used, for example, in large astronomic telescopes. Furthermore, an adaptive optical unit usually compensates for the optical aberrations due to atmospheric disturbances. In practice, these aberrations are detected and corrected within a few seconds using deformable mirrors. However, to further improve the performance of these optical systems, dynamic disturbances in the mechanics, i.e. small movements and deformations of the optical surfaces, must also be taken into account. For the investigation of such cases, multidisciplinary simulation methods are developed and presented.