The demand for polyester fiber is increasing gradually day by day. Because of its good strength, low manufacturing cost, and ease of modification, polyester fiber has distinct characteristics, whereas cotton is well known for its comfort. Blending these fibers improves the performance of yarns. In this study, cotton/polyester was blended in different ratios to evaluate yarn performance. Three groups of yarn: rigid, core, and dual-core-spun, have been produced to examine the yarn’s performance. From the study, it has been found that increasing the polyester blend ratio increases the yarn strength and elongation but decreases the yarn unevenness and imperfections. Among the group, having more core components decreases yarn strength, unevenness, and imperfection but increases elongation. From the statistical analysis, except strength, all other properties have good interaction on yarn type and blending ratio. Pearson correlation also indicated that elongation and hairiness have a good correlation with yarn type where, except for hairiness, all other properties have shown a strong positive correlation on blending ratio.