As shown through an inventory of the procedures used in diverse forms of qualitative content analysis projects, the logic of qualitative procedures is in most cases not standardized. Often researchers pay little or no attention to the procedures which they apply. This contribution presents and discusses a procedure for interpretive content analysis which was applied in an empirical study into trans-border news coverage in the Dutch-German Euregion Rhine-Waal. First, we will describe the study on the portrayal of the Dutch and German people as well as their respective countries, The Netherlands and Germany, in the four main regional newspapers of this region. Secondly, basic principles of qualitative methodology are discussed and, thirdly, the procedure of the applied method based on these principles is presented and illustrated by means of exemplary material. Finally, after a brief presentation of some empirical results, the applied procedure of interpretive content analysis is discussed.