At the 2006 conference of the International Society for Humor Studies (Danish University of Education, Copenhagen), several panels addressed issues raised by the Muhammad cartoon story. Among these, a colloquium organized by Paul Lewis and decorously titled “Transnational Ridicule and Response” focused on the implications for humor research of the events surrounding the publication of the cartoons. Along with other materials, panelists were encouraged to review summaries of and timelines for the story available from the BBC and Wikipedia. Of the questions considered by panelists, the following drew interesting and, at times, provocative responses: Were the cartoons humorous; if so, did they represent a distinct or new kind of humor? Were the modes of global transmission of the cartoons new? Does the story have implications for ongoing humor research and advocacy? The goal was to approach the controversy not as partisans with particular political outlooks but as students of humor. The brief essays collected here were written following the conference by members of the panel (Christie Davies, Giselinde Kuipers, Paul Lewis, and Victor Raskin) and by two others who attended the colloquium (Elliott Oring and Rod A. Martin). After reviewing the essays, HUMOR editor Salvatore Attardo suggested that each of the participants be invited to read what the others had written and submit a brief response. Responses included here were received from Davies, Kuipers, Lewis, Oring, and Raskin.