Around the world, idiopathic scoliosis accounts for the majority of occurrences of adolescent scoliosis. The absence of underlying congenital or neuromuscular problems distinguishes adolescent idiopathic scoliosis (AIS), which affects children ages 13 to 18, from other kinds of scoliosis. The prevalence of AIS is influenced by a number of variables, such as physical activity, gender, backpacks, body mass index, and others. AIS has an impact on the child’s development not just physically but also psychologically, emotionally, and mentally. This study used nationwide databases to describe the prevalence of adolescent idiopathic scoliosis and associated risk variables. The current review analysis showed that AIS was significant worldwide and that adolescent gender, physical activity, body mass index, backpack carrying and backpack weight were all significant risk factors for developing AIS.