Injection molding is widely used to process short fibre reinforced thermoplastics. The quality and especially the mechanical properties of the resulting part are linked to the mold conception (for example the gate(s) and the venting port(s) locations) and to the processing parameters which will govern fibre orientation distribution. Fibre orientation modelling is based on the well known Folgar and Tucker equation. The models differ one from another by the interaction parameter, the closure approximation and by the coupling with the rheology of the reinforced melt. Quantitative comparison with experiments is very tedious and generally limited to simple part geometries (plaque or disk). As a consequence, in complex geometries, fibre orientation distribution is experimentally checked using several techniques and the resulting anisotropic thermo-mechanical properties are computed using various homogenization theories. In this paper, we propose a first integrated approach of the injection molding of fibre reinforced thermoplastics starting from rheology of the material, orientation equation, interaction parameter and closure approximation. The resulting local fibre orientation distribution is then used in two ways in order to predict the mechanical properties of the part: first, using classical analytical homogenization theories, but based on the computed orientation tensor and not on an experimental one, and then, using numerical homogenization which consists in generating a Representative Elementary Volume (REV), determining its unidirectional mechanical properties and finally, in computing directly the anisotropic properties of the part.