The start up physics studies SPS of the Second Egyptian Research Reactor is presented in this work. The SPS consists of the approach to criticality, the power and flux distribution of the first critical core, criticality, power and flux distribution of the working core. The working core is the beryllium-reflected core with cobalt loaded for irradiation. Some of the neutronic parameters are determined, these parameters are the power peaking factor, power distribution, the excess reactivity for both the water and beryllium reflector cores, the core excess reactivity with the cobalt loaded, the reactivity worth of the cobalt irradiation box. Flux distribution for one fast, three eipthermal and one thermal energy group are also determined. All the above neutronic parameters are calculated by using the lattice cell code WIMSD4 and the two dimensional diffusion code DIXY2.